Protein Alignment Rfx and rfx3

DIOPT Version :10

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_073770240.1
• Gene: rfx3 / 570989
• ZFINID: ZDB-GENE-061103-253
• Length: 787
• Species: Danio rerio
• Alignment Length: 789
• Identity: 342/789 - (43%)
• Similarity: 427/789 - (54%)
• Gaps: 157/789 - (19%)

  Fly   154 TTEPNGTTVTHSIPIHSMADLAAIKDGVDLAQQVANGQVTVVQTTEDDDGTPFITVTVSGQEQNY 218
            |.|....:...::|:.:...:.....|    ||||: ||.|.|..:          ||...:..|
Zfish    25 TPEAGADSTVSTVPLQTSVPVQPAVSG----QQVAS-QVPVQQQAQ----------TVQQVQHVY 74

  Fly   219 --QVQYVDSELYHSNSSQTQMT---YPFCPVGDYQGNGQTAYYSTTGQYG---------TTSSAG 269
              |||||..|   :||..|..|   |.:.....|..|....|:.|.|..|         :|.|..
Zfish    75 QAQVQYVQEE---NNSVYTNGTIRAYSYSEPQLYNQNSSGNYFDTQGGGGSAAQVSTVVSTHSMA 136

  Fly   270 GSSNG----AHSTTLPYLVPVEEGILLNGSAHSLSQSQSQSHGRDSPHSLTVSSRDWERDADRVN 330
            .:.||    |...|...::......|:.|:    |...|..||.
Zfish   137 NNGNGTGALAMGLTGGQIISSSGAYLIGGN----SMDGSAPHGA--------------------- 176

  Fly   331 GTNRHWVQEVAYIQEAQSTPQTPTSTTTTHSASGGSLGTGGGGASPDSDQSALGSSNKIASATIK 395
                        .|..:::|.|......|...|.|.          .|.:|:|.:|:      ::
Zfish   177 ------------AQTTRASPATIEMAIETLQKSEGL----------SSQRSSLLNSH------LQ 213

  Fly   396 WLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYH 460
            ||..|||||:|||||||||||||::||.|.||:|||||||||||||:|.||||||||||||||||
Zfish   214 WLLDNYETAEGVSLPRSTLYNHYLRHCQEQKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYH 278

  Fly   461 YYGIRIKPGSLLNSQAMDDKQMLAAGYGP-----------SSDGTGGPGSGPMVSVTSSTAGQLT 514
            |||||:||.|.|| :..:|.|.:|....|           ..||..|.        ..|:|||
Zfish   279 YYGIRVKPDSPLN-RLQEDMQYMALRQQPVQQKQRFKPVQKMDGVSGD--------NFSSAGQ-- 332

  Fly   515 GSNGLGGGHGQRHSNGTKKHTFKPETYEACIQYIGDGTSALPSFPPIELNHSFNSELTLEDVDTF 579
                        |:....:.||..::...  |...||:.|||.|..::|..:.:. :..|||...
Zfish   333 ------------HTPNAAEQTFIAQSQHH--QQFLDGSRALPEFVELDLGEAVDG-VGPEDVKAL 382

  Fly   580 RGLYREHCESFLDAVLNLEFNTVEFLLRDFWRAS-----------DNNNLDECEEEKYLSKTKLY 633
            :.|||||||:.||.|:||:||.:|.|.:.|||.|           :|:.|.|.|..  |.:.:|.
Zfish   383 QTLYREHCEAILDVVVNLQFNLIENLWQTFWRYSASSSVEGVTITENSGLSEIEGR--LPRARLI 445

  Fly   634 LLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLEIWLCESMLGVPEQL 698
            |||....|.|::...|:..||..|:::||||||.||:|||||||||||:||.||..:|..:|.::
Zfish   446 LLCRHEAVHKWMNTCDHLMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLTNAMSSIPPRM 510

  Fly   699 AQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRVDFHNVQEQAAWVSQCAP 763
            ...|.||||||.||||||||||||||||||||||.:||:|||||||||||.||||||:||.||..
Zfish   511 INTKVSAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCEE 575

  Fly   764 AVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYNGKPTYARAARQFLLKWSFYSSMIIRD 828
            .||||||.||||.|||||||||||:||..||...::.|..|||..:|||||||||||||||:|||
Zfish   576 GVVQRLEQDFKATLQQQSSLEQWAAWLDNVVTQILKPYEDKPTLPKAARQFLLKWSFYSSMVIRD 640

  Fly   829 LTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQDKTAIAVICE------------------RM 875
            ||||||:|||||||||||:||||||||||::|:|..:|||.|:.|                  .|
Zfish   641 LTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETAIGVMGEFQDLNTMSPANIDKDEVSEM 705

  Fly   876 KKDMDFEFE 884
            ..|:|.|.|
Zfish   706 DSDLDEEME 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	392..468	CDD:460512	60/75 (80%)
rfx3	XP_073770240.1	None