Protein Alignment Rfx and Rfx4

DIOPT Version :10

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: XP_038936002.1
• Gene: Rfx4 / 500818
• RGDID: 1562092
• Length: 757
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 193/601 - (32%)
• Similarity: 276/601 - (45%)
• Gaps: 126/601 - (20%)

  Fly   306 SHGRDSPHSLTVSSRDWERDADRVNGTNRHWVQEVAYIQEAQSTPQTPTSTTT-----------T 359
            :.||:        .|||||...:.      |.::..|   .|..|..|.||.:           .
  Rat     3 NQGRE--------KRDWERMESKA------WARDGGY---RQRRPWQPHSTESWIERCLNESENK 50

  Fly   360 HSASGGSLGTGGGGASPDSDQSALGSSNKIAS-----ATIKWLSRNYETADGVSLPRSTLYNHYM 419
            ..:|..|||      :..:|::....:|:.:.     ||::||..|||.|:||.:|||.||.||:
  Rat    51 RYSSHTSLG------NVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYL 109

  Fly   420 QHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLA 484
            ..|.::..:|||||||||:||..|..|.||||||||.||||||||.:|..|          |...
  Rat   110 DFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESS----------QYYD 164

  Fly   485 AGYGPSSDGTGGPGSGPMVSVTSSTAGQLTGSNGLGGGHGQRHSNGTKKHTFKPETYEACIQYIG 549
            ..|  |..|...........||..|.           .:..|...||
  Rat   165 VMY--SKKGAAWVSETGKREVTKQTV-----------AYSPRSKLGT------------------ 198

  Fly   550 DGTSALPSFPPI-ELNHSFNSELTLEDVDTFRGLYREHCESFLDAVLNLEFNTVEFLLRDFWRAS 613
                .||.||.: :||  ..:.|..|.|.||..:||.||:..||.|:...|:.|:..|..||:..
  Rat   199 ----LLPDFPNVKDLN--LPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGM 257

  Fly   614 DNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRN 678
            ..:.|.               :...:.|...|...|...|:....|::|.||:::|::|||.||.
  Rat   258 PPHMLP---------------VLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRK 307

  Fly   679 FAKNLEIWLCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDL 743
            |||.|:.||..::..:||.|..||......|.|.|||.||||||.||:|.|:.:.....|||.|.
  Rat   308 FAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDW 372

  Fly   744 NRVDFHNVQEQAAWVSQCA----PAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYNGK 804
            ..||..::.:|..:..:.:    ..::.:|..:|...|::||.:|.:..||..:|:..:.:...|
  Rat   373 RNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAK 437

  Fly   805 --PTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEH---------- 857
              .:..:.|:||||.||.:.:.:|||:||.||.||||||||.|:||:|:.||:|.
  Rat   438 RQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANEL 502

  Fly   858 --------KIAEAQDK 865
                    ..||||::
  Rat   503 MRAMKGEGSTAEAQEE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	392..468	CDD:460512	47/75 (63%)
Rfx4	XP_038936002.1	RFX_DNA_binding	80..158	CDD:460512	47/77 (61%)