Protein Alignment Rfx and Rfx6

DIOPT Version :10

• Sequence 1: NP_001247023.2
• Gene: Rfx / 41266
• FlyBaseID: FBgn0020379
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: NP_001401847.1
• Gene: Rfx6 / 294395
• RGDID: 1307491
• Length: 923
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 192/668 - (28%)
• Similarity: 297/668 - (44%)
• Gaps: 127/668 - (19%)

  Fly   277 STTLPYLVPVEEGILLNG---------SAHSLSQSQSQSHGRDSPHSLTVSSRDWERDADRVNGT 332
            |..||..:..|.|..|.|         ||:.::.::| |..:|....|.|..:      ..::..
  Rat    17 SPQLPSEIAEECGAQLLGKGLLVYSEESAYLVASARS-SEEKDGDLGLQVGVK------SEMHLN 74

  Fly   333 NRHWVQEVAYIQEAQSTPQTPTSTTTTHSASGGSLGTGGGGASPDSDQSALGSSNKIASATIKWL 397
            |.::..|    ::...|.::.|..|....:...|:            ...:....|....|::||
  Rat    75 NGNFSSE----EDDADTQESKTKATDPQLSQKKSI------------TQIMKDKKKQTQLTLQWL 123

  Fly   398 SRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYY 462
            ..||...:||.|||..||.||:..|.:.||||..||:|||.||..|..|.||||||||:||||||
  Rat   124 EDNYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYY 188

  Fly   463 GIRIKPGSLLNSQAMDDKQMLAAGYGPSSDGTGGPGSGPMVSVTSSTAGQLTGSNGLGGGHGQRH 527
            ||.||..|              |.|.....|.|         :|..:..:|....|.
  Rat   189 GIGIKESS--------------AYYHSVYSGKG---------LTRFSGSKLKNEGGF-------- 222

  Fly   528 SNGTKKHTFKPETYEACIQYIGDGTSALPSFPPIELNHSFNSELTLEDVDTFRGLYREHCESFLD 592
               |:|::...:|          || .||.||..: :..:...:..:.|||...:|:.||:..||
  Rat   223 ---TRKYSLSSKT----------GT-LLPEFPSAQ-HLVYPGCIAKDKVDTLIMMYKTHCQCILD 272

  Fly   593 AVLNLEFNTVEFLLRDFWRASDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTV 657
            ..:|..|..::..|..||:...::.|...|....:.     :.|.|          |...|:...
  Rat   273 NAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIID-----IFCVC----------DSILYKVLT 322

  Fly   658 DVIIPDVLRSIPNALTQAIRNFAKNLEIWLCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHL 722
            ||:||..::.:|.:|...|||||||.|.|:..|:..:||.|...|...:..|..:|:|.||..||
  Rat   323 DVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKIPILRRFVSSLKRQTSFLHL 387

  Fly   723 AQAARAVLQNGAQISQMLSDLNRVDFHNVQEQAAWVSQCAPAVVQRLESDF---------KAALQ 778
            ||.||..|.:...::.|:||:.:||.:::..||......:......:.|::         |..|:
  Rat   388 AQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEYDSITVFQELKDLLK 452

  Fly   779 QQSSLEQWASWLQLVVES---AMEEYNGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSF 840
            :.:::|.:..||..|||.   .|.:.||: :..:.|:.|||||||:.:.::.:|||.:||||||.
  Rat   453 KNATVEAFIEWLDTVVEQRVIKMSKQNGR-SLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSL 516

  Fly   841 HLIRLLFDEYMFYLVEHKIAEAQDKTAIAVICERMKKDMDFEFECQFAYITSDTEHQTTPS---- 901
            ||||:|.|||:...:|.:....:::....::.:.||..     |...|..|:      :||
  Rat   517 HLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNS-----EASKAAFTA------SPSSCFL 570

  Fly   902 ------SASSGGDVGNEA 913
                  |:.|...|.||:
  Rat   571 ANRNKGSSLSSDPVKNES 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rfx	NP_001247023.2	RFX_DNA_binding	392..468	CDD:460512	45/75 (60%)
Rfx6	NP_001401847.1	RFX_DNA_binding	119..194	CDD:460512	45/74 (61%)
		PTZ00395	<652..>758	CDD:185594