Protein Alignment CG42795 and Tbc1d10c

DIOPT Version :10

• Sequence 1: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_001075449.1
• Gene: Tbc1d10c / 361697
• RGDID: 1311490
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 143/561 - (25%)
• Similarity: 198/561 - (35%)
• Gaps: 176/561 - (31%)

  Fly   157 GSNNRSPSSTKTTMLTRNG--GGHGTSPTASGSGHAPSATAAADDEATSDYNQW----LHAMKLV 215
            ||::....|:......|.|  ||:...   .|.|..|:      |.......:|    ||..|.:
  Rat    23 GSDSEISGSSPYRQADRYGFIGGNSAE---LGLGQPPA------DLIRQREMKWVEMTLHWEKTM 78

  Fly   216 AR--------LPGGTPPEFRRKLWLSLADKYLKSKNVDWAQQREKCFC---EEWREDDEELGIQI 269
            :|        ...|.|...|.:.|..|...::..||.....| |....   .:|.|       .|
  Rat    79 SRRYKKVKIQCRKGIPSALRARCWPLLCGAHMCQKNNPGTYQ-ELAVAPGDPQWME-------TI 135

  Fly   270 VKDLHRTG--SNLCTGPAGSINQAKLKRILLGYARYNPEVGYCQGFNMLGALILQVMDKEEEESM 332
            .:||||..  ..:...|.|. .|..|.::|..|..|.||.||||....:.|::|  |....||:.
  Rat   136 GRDLHRQFPLHEMFVSPQGH-GQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLL--MHLPPEEAF 197

  Fly   333 KVMIYLVEGVLPTGYFYGSMGGLQADMGVFRELMQTRLPRLAKHLQRL-QGPVENAFEPPLTNVF 396
            ..::.:.|..|| ||:...|..:|.|..||..|::..|||:.||||:: .||:          ::
  Rat   198 WCLVQICEVYLP-GYYGPHMEAVQLDAEVFMALLRRLLPRVYKHLQQVGVGPL----------LY 251

  Fly   397 TMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRTALVLWSLLEERVISVRSADEFYGKMGSYS 461
            ..:|||.:|...||...|||:||..|.||:.||.|..|.|..|
  Rat   252 LPEWFLCLFTRSLPFPIVLRIWDAFLSEGAKVLFRAGLTLMRL---------------------- 294

  Fly   462 SELLNGHLVDSNGLIE-RVVKLGPIEDLRQLRDKHLYNIAPLRHKQGLQLYYDEEDTHSDEERLA 525
                      :.|.:| |....|.:|.|..||     .|.|               |...||
  Rat   295 ----------ALGTVEQRTACPGLLETLGALR-----TIPP---------------TQLQEE--- 326

  Fly   526 VATVFGLNWGRRGSVGPAAAGKQQVEQKDRLALDISLLKKQYDRLRERQKQAHVILTTACSTAAR 590
               ||                   :.|...:||.            ||..|..:.:..|
  Rat   327 ---VF-------------------MSQVHNVALS------------ERDLQREIRIQLA------ 351

  Fly   591 QGSGPASSSQPAVPVNQLLL-GRPAIVTNK---GKRVGAPLGAIPPARKPSLPAVL-----HTKP 646
              ..|.||..| ||:.|..| |..||..::   |.|.||         ||.:|.::     ...|
  Rat   352 --QLPKSSPGP-VPLPQARLPGAQAIFESQQLAGMRGGA---------KPEIPRIVVQPPEEPNP 404

  Fly   647 TSEKQLRRGET---LLWRD-----TDPSRRRRDSLTWKEIK 679
            ...|...||:|   ||.|.     ..|||..|.|.::.:.:
  Rat   405 PRRKPQTRGKTFHGLLIRARGPPIEGPSRSHRGSASFLDTR 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855	63/177 (36%)
		DUF4682	560..689	CDD:464830	35/137 (26%)
		PTZ00121	<1112..2009	CDD:173412
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628
Tbc1d10c	NP_001075449.1	TBC	89..294	CDD:214540	73/226 (32%)