Protein Alignment CAH7 and CA8

DIOPT Version :10

• Sequence 1: NP_649979.1
• Gene: CAH7 / 41238
• FlyBaseID: FBgn0037788
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_001399060.1
• Gene: CA8 / 767
• HGNCID: 1382
• Length: 306
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 81/304 - (26%)
• Similarity: 135/304 - (44%)
• Gaps: 85/304 - (27%)

  Fly    21 EWGYPDLDNNQDEPFPKWGGLCD--SGKKQSPINLHVKGALKGEFDALKFENYDEHQKNLRM--- 80
            ||||        |...:||.:..  :|:.||||||:.:.|           .||....::|:
Human    28 EWGY--------EEGVEWGLVFPDANGEYQSPINLNSREA-----------RYDPSLLDVRLSPN 73

  Fly    81 ---------VNNGHSIQLSGFDHELTLSGGALLQ--DFVVEQIHMHW------WSEHTINDIRYP 128
                     .|:||:||:. ...:..||||.|.|  :|.:.::..||      .||||:|...:|
Human    74 YVVCRDCEVTNDGHTIQVI-LKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFP 137

  Fly   129 LEVHIVHRN-TIYPNMTMAANFKDGIVVIGVLYHV--SNTPNEAIGSIIKSL---GAVKSYDSMN 187
            :|:|::|.| |::.::..|.....||.:|.:...:  .:...:|:..|::.:   |..|:....|
Human   138 MELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFN 202

  Fly   188 KPVLVADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQ------------- 239
            ...|:.|        |.:.:|:.|.||||.|.|:|.||||:.  .:|:|:.|
Human   203 PNTLLPD--------PLLRDYWVYEGSLTIPPCSEGVTWILF--RYPLTISQLQVWRMESGRKVG 257

  Fly   240 -----VNEFKEI-------EYDEGKQ--LHNNYRELQSENNRAV 269
                 :.||:.:       |..||..  |.:|:|..|..::|.:
Human   258 MPVISIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVI 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_649979.1	Carb_anhydrase	38..269	CDD:459707	76/285 (27%)
CA8	NP_001399060.1	alpha_CARP_VIII	35..305	CDD:239394	76/289 (26%)