Protein Alignment CAH7 and CA2

DIOPT Version :10

• Sequence 1: NP_649979.1
• Gene: CAH7 / 41238
• FlyBaseID: FBgn0037788
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_000058.1
• Gene: CA2 / 760
• HGNCID: 1373
• Length: 260
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 85/273 - (31%)
• Similarity: 140/273 - (51%)
• Gaps: 41/273 - (15%)

  Fly    19 ANEWGYPDLDN----NQDEPFPKWGGLCDSGKKQSPINLHVKGALKGEFD-ALK--FENYDEHQK 76
            ::.|||...:.    ::|.|..|       |::|||:::....|   ::| :||  ..:||: ..
Human     2 SHHWGYGKHNGPEHWHKDFPIAK-------GERQSPVDIDTHTA---KYDPSLKPLSVSYDQ-AT 55

  Fly    77 NLRMVNNGHSIQLSGFD---HELTLSGGALLQDFVVEQIHMHW------WSEHTINDIRYPLEVH 132
            :||::||||:..:. ||   .:..|.||.|...:.:.|.|.||      .||||::..:|..|:|
Human    56 SLRILNNGHAFNVE-FDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELH 119

  Fly   133 IVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLA 197
            :||.||.|.:...|....||:.|:|:...|.:. ...:..::..|.::|:....      ||...
Human   120 LVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSA-KPGLQKVVDVLDSIKTKGKS------ADFTN 177

  Fly   198 VD--DLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEIEYD-EGKQ---LHN 256
            .|  .|:|...:|:||.||||||...|.||||||.|...|:.:||.:|:::.:: ||:.   :.:
Human   178 FDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVD 242

  Fly   257 NYRELQSENNRAV 269
            |:|..|...||.:
Human   243 NWRPAQPLKNRQI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_649979.1	Carb_anhydrase	38..269	CDD:459707	79/248 (32%)
CA2	NP_000058.1	alpha_CA_I_II_III_XIII	1..259	CDD:239393	85/273 (31%)