Protein Alignment CAH7 and Ca3

DIOPT Version :10

• Sequence 1: NP_649979.1
• Gene: CAH7 / 41238
• FlyBaseID: FBgn0037788
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_062165.2
• Gene: Ca3 / 54232
• RGDID: 2241
• Length: 260
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 80/279 - (28%)
• Similarity: 117/279 - (41%)
• Gaps: 53/279 - (18%)

  Fly    19 ANEWGYPDLDNNQDEPFPKWGGL--CDSGKKQSPINLHVKGALKGEFDALKFENYDEHQKNLR-- 79
            |.||||  ..:|..|   .|..|  ...|..||||.||.|..              .|..:|:
  Rat     2 AKEWGY--ASHNGPE---HWHELYPIAKGDNQSPIELHTKDI--------------RHDPSLQPW 47

  Fly    80 -----------MVNNGHSIQL---SGFDHELTLSGGALLQDFVVEQIHMHW------WSEHTIND 124
                       ::|||.:.::   ..||..: |.||.|...:.:.|.|:||      .||||::.
  Rat    48 SVSYDPGSAKTILNNGKTCRVVFDDTFDRSM-LRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDG 111

  Fly   125 IRYPLEVHIVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKP 189
            ::|..|:|:||.|..|.....|....|||.|:|:...:.....| ...::.:|..:|: .....|
  Rat   112 VKYAAELHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGE-FQILLDALDKIKT-KGKEAP 174

  Fly   190 VLVADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNE----FKEIEYDE 250
            ....|...   |.|:..:|:||.||.|||.|.|.:.|::|.|...|:.||:.:    |...|.:.
  Rat   175 FNHFDPSC---LFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEP 236

  Fly   251 GKQLHNNYRELQSENNRAV 269
            ...|..|:|..|....|.|
  Rat   237 PVPLVGNWRPPQPIKGRVV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_649979.1	Carb_anhydrase	38..269	CDD:459707	72/258 (28%)
Ca3	NP_062165.2	alpha_CA_I_II_III_XIII	1..259	CDD:239393	80/279 (29%)
		Involved in proton transfer. /evidence=ECO:0000250|UniProtKB:P07451	64..67		0/2 (0%)