Protein Alignment CAH7 and CA13

DIOPT Version :10

• Sequence 1: NP_649979.1
• Gene: CAH7 / 41238
• FlyBaseID: FBgn0037788
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_940986.1
• Gene: CA13 / 377677
• HGNCID: 14914
• Length: 262
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 80/281 - (28%)
• Similarity: 133/281 - (47%)
• Gaps: 62/281 - (22%)

  Fly    22 WGYPDLDN--NQDEPFPKWGGLCDSGKKQSPINLHVKGALKGEFDALKFEN--------YDEHQK 76
            |||.:.:.  :..|.||    :.| |.:||||.:..|        .:|:::        ||....
Human     6 WGYREHNGPIHWKEFFP----IAD-GDQQSPIEIKTK--------EVKYDSSLRPLSIKYDPSSA 57

  Fly    77 NLRMVNNGHSIQLSGFD---HELTLSGGALLQDFVVEQIHMHW------WSEHTINDIRYPLEVH 132
            .: :.|:|||..:. ||   ::..|.||.|...:.:.|:|:||      .|||.::.:.|..|:|
Human    58 KI-ISNSGHSFNVD-FDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH 120

  Fly   133 IVHRNT-IYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVK---------SYDSMN 187
            :||.|: .||:...||:..||:.|:||...:.. ||..:..|..:|.::|         ::|.::
Human   121 VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGE-PNSQLQKITDTLDSIKEKGKQTRFTNFDLLS 184

  Fly   188 KPVLVADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEI----EY 248
                         |:|...:|:||.||||.|...|:||||||.:...::..|:.:|:.:    |.
Human   185 -------------LLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEG 236

  Fly   249 DEGKQLHNNYRELQSENNRAV 269
            :....|.:|:|..|....|.|
Human   237 EAAAFLVSNHRPPQPLKGRKV 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_649979.1	Carb_anhydrase	38..269	CDD:459707	73/261 (28%)
CA13	NP_940986.1	alpha_CA_I_II_III_XIII	2..261	CDD:239393	80/281 (28%)