Protein Alignment CAH7 and Car14

DIOPT Version :10

• Sequence 1: NP_649979.1
• Gene: CAH7 / 41238
• FlyBaseID: FBgn0037788
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: XP_006501505.1
• Gene: Car14 / 23831
• MGIID: 1344341
• Length: 460
• Species: Mus musculus
• Alignment Length: 322
• Identity: 95/322 - (29%)
• Similarity: 147/322 - (45%)
• Gaps: 39/322 - (12%)

  Fly     1 MHLIALSLIVCCSVSFSWANEWGY--PDLDNNQDEPFPKWGGLCDSGKKQSPINLHVKGALKGEF 63
            |...||.|.|...::....:.|.|  |...::....:|:.|     |..|||||:.....:   |
Mouse     1 MLFFALLLKVTWILAADGGHHWTYEGPHGQDHWPTSYPECG-----GDAQSPINIQTDSVI---F 57

  Fly    64 D----ALKFENYDE-HQKNLRMVNNGHSIQLSGFDHELTLSGGALLQDFVVEQIHMHW------- 116
            |    |::...||: ..:.|.:.||||::|||   ...||..|.|.:.:...|:|:||
Mouse    58 DPDLPAVQPHGYDQLGTEPLDLHNNGHTVQLS---LPPTLHLGGLPRKYTAAQLHLHWGQRGSLE 119

  Fly   117 WSEHTINDIRYPLEVHIVHRNT-IYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAV 180
            .|||.||......|:|:||.:: .|.:::.||....|:.|:|:|..|..|.|.|...|:..|..:
Mouse   120 GSEHQINSEATAAELHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEI 184

  Fly   181 KSYDSMNKPVLVADSLAVDDLVP-SVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFK 244
            :..|....    ....:|.:|.| .:|.:|.|.||||||.|.::|.|.|......:::.|:.:.:
Mouse   185 RYKDQKTS----VPPFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQ 245

  Fly   245 E----IEYDEGKQLHNNYRELQSENNRAV---VLVEQPEQRSGS-AGLTASVSLGLMTLILA 298
            |    .|.|..:.|..|||..|..|.|.:   .:...|...:|. .||...:..|.:.|:||
Mouse   246 ETLSSTEEDPSEPLVQNYRVPQPLNQRTIFASFIQAGPLYTTGEMLGLGVGILAGCLCLLLA 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_649979.1	Carb_anhydrase	38..269	CDD:459707	78/248 (31%)
Car14	XP_006501505.1	alpha_CA_XII_XIV	29..278	CDD:239400	79/263 (30%)