| Sequence 1: | NP_649945.1 | Gene: | topi / 41199 | FlyBaseID: | FBgn0037751 | Length: | 814 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003404.1 | Gene: | ZIC3 / 7547 | HGNCID: | 12874 | Length: | 467 | Species: | Homo sapiens |
| Alignment Length: | 530 | Identity: | 107/530 - (20%) |
|---|---|---|---|
| Similarity: | 162/530 - (30%) | Gaps: | 196/530 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 210 YDLATGIESSRKNAAKGPNECTMCDRKFVHASGLVRHMEKHALDLIPSQTSEQPHT--IPAAGLH 272
Fly 273 VVVKCNSCGRIFYDPQVA---------FRHGLIHDSEHSTMRQSPMTQVPS-------------- 314
Fly 315 ----NRADFNE--LLLDGEMLIDNDPAFATSNQNTNPPKKEMFSSLILGSVLQCEFCEYIFADIA 373
Fly 374 ELLVHSASHVAERRFECTACDIQMNTAKEASIHFQTDCIF--MREAIRSLNVTLSRYFVCNVCEL 436
Fly 437 KFANTDLLQEHRCTSFHYFPRLNENGKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKKKREKETR 501
Fly 502 NTGAGRIRQYLC--DIC---GKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIR 561
Fly 562 KCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPY 626
Fly 627 SCLFCTKTFRQRGDRDKHIRARHSH--------------------LDANSRLMMQMQKFQLET-A 670
Fly 671 AAQKAQSHNP 680 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| topi | NP_649945.1 | C2H2 Zn finger | 230..250 | CDD:275368 | 3/19 (16%) |
| C2H2 Zn finger | 277..297 | CDD:275368 | 5/28 (18%) | ||
| C2H2 Zn finger | 431..453 | CDD:275368 | 3/21 (14%) | ||
| COG5048 | <450..647 | CDD:227381 | 50/201 (25%) | ||
| C2H2 Zn finger | 469..490 | CDD:275368 | 5/20 (25%) | ||
| zf-C2H2 | 511..533 | CDD:278523 | 8/26 (31%) | ||
| C2H2 Zn finger | 513..564 | CDD:275368 | 18/55 (33%) | ||
| C2H2 Zn finger | 541..561 | CDD:275368 | 5/19 (26%) | ||
| zf-H2C2_2 | 555..581 | CDD:290200 | 8/25 (32%) | ||
| C2H2 Zn finger | 572..592 | CDD:275368 | 1/19 (5%) | ||
| zf-H2C2_2 | 585..609 | CDD:290200 | 5/23 (22%) | ||
| zf-C2H2 | 598..620 | CDD:278523 | 7/21 (33%) | ||
| C2H2 Zn finger | 600..620 | CDD:275368 | 6/19 (32%) | ||
| zf-H2C2_2 | 612..637 | CDD:290200 | 10/24 (42%) | ||
| C2H2 Zn finger | 628..646 | CDD:275368 | 5/17 (29%) | ||
| ZIC3 | NP_003404.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 66..107 | 12/61 (20%) | |
| Nuclear localization signal | 297..322 | 8/24 (33%) | |||
| C2H2 Zn finger | 302..322 | CDD:275368 | 7/19 (37%) | ||
| SFP1 | <324..408 | CDD:227516 | 32/110 (29%) | ||
| C2H2 Zn finger | 330..352 | CDD:275368 | 5/22 (23%) | ||
| Nuclear localization signal | 330..352 | 5/22 (23%) | |||
| C2H2 Zn finger | 360..382 | CDD:275368 | 8/47 (17%) | ||
| C2H2 Zn finger | 390..410 | CDD:275368 | 5/19 (26%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 404..467 | 14/60 (23%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||