Protein Alignment topi and LOC3291310

DIOPT Version :10

• Sequence 1: NP_649945.1
• Gene: topi / 41199
• FlyBaseID: FBgn0037751
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_061509887.1
• Gene: LOC3291310 / 3291310
• VectorBaseID: AGAMI1_010257
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 225
• Identity: 63/225 - (28%)
• Similarity: 97/225 - (43%)
• Gaps: 34/225 - (15%)

  Fly   427 RYFVCNVCELKFANTDLLQEHRCTSFHYFPRLNENGKKLLL-PCDFCDVNFEFAHDFLAHSEEKH 490
            |.::|:.|.:      |:.:        .||...|..||:. .|..|.|......:.|.|.|..|
Mosquito   254 RKYLCDTCGV------LIND--------LPRHTLNHSKLIKHACPHCPVEMVEYSNLLRHIEAVH 304

  Fly   491 LNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLRFHQGV-KPFVCQEENCDRKFTIRP 554
                  ||..|.:         |::|||.:|.::.|..|:..|.|: ....|:.  |.:.|....
Mosquito   305 ------EKRIRKS---------CELCGKGFTHNNSLVSHMVVHHGIGDTHKCKV--CPKVFRHAS 352

  Fly   555 DLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRI 619
            .|..|::|||:....:.|.:||..|.:.....:|...|..||.|||.||||||....|.:.|::.
Mosquito   353 GLRGHVKKCHSNATKFECSLCGAFFSSRYDLKKHGRSHSSERPYECSECGKRFKSQYARRIHEQA 417

  Fly   620 HTGEKPYSCLFCTKTFRQRGDRDKHIRARH 649
            |:| ..|.|..|.:.:|.:.....|::..|
Mosquito   418 HSG-LLYECDVCRRPYRYKALMRMHMKRTH 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
topi	NP_649945.1	C2H2 Zn finger	230..250	CDD:275370
		C2H2 Zn finger	277..297	CDD:275370
		C2H2 Zn finger	431..453	CDD:275368	3/21 (14%)
		COG5048	<450..647	CDD:227381	58/198 (29%)
		C2H2 Zn finger	469..490	CDD:275368	6/20 (30%)
		C2H2 Zn finger	513..564	CDD:275368	15/51 (29%)
		C2H2 Zn finger	541..561	CDD:275368	5/19 (26%)
		C2H2 Zn finger	572..592	CDD:275368	5/19 (26%)
		C2H2 Zn finger	600..620	CDD:275368	9/19 (47%)
		zf-H2C2_2	612..637	CDD:463886	7/24 (29%)
		C2H2 Zn finger	628..646	CDD:275368	4/17 (24%)
LOC3291310	XP_061509887.1	None