DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9471 and Nsdhl

DIOPT Version :9

Sequence 1:	NP_001097729.1	Gene:	CG9471 / 41197	FlyBaseID:	FBgn0037749	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_035071.3	Gene:	Nsdhl / 18194	MGIID:	1099438	Length:	362	Species:	Mus musculus

Alignment Length:	168	Identity:	36/168 - (21%)
Similarity:	66/168 - (39%)	Gaps:	59/168 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 QRIAIIGGTGMTGECAVDHALQKGLSVKLLYRSEKTVPERFKS-KVELVKGDVTNYEDVQRVIEG 65
            ::..:|||:|..|:..|:..|::|.:|.:.     .:.:.|.: :|:...||:.|.:|:...::|
Mouse    27 KKCTVIGGSGFLGQHMVEQLLERGYTVNVF-----DIHQGFDNPRVQFFIGDLCNQQDLYPALKG 86

  Fly    66 VDAV------------------AVILGTRNKLEATTE--------------------LSRGTENL 92
            |..|                  ...:||:..:|...|                    :..|||:|
Mouse    87 VSTVFHCASPPPYSNNKELFYRVNFIGTKTVIETCREAGVQKLILTSSASVVFEGVDIKNGTEDL 151

  Fly    93 IKAMK------EAKLTKFSIVM------SSFL---LRP 115
            ..|||      |.|:.:...|:      .:||   :||
Mouse   152 PYAMKPIDYYTETKILQERAVLDANDPKKNFLTAAIRP 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9471	NP_001097729.1	BVR-B_like_SDR_a	3..197	CDD:187555	36/167 (22%)
CG9471	NP_001097729.1	WcaG	3..>110	CDD:223528	32/157 (20%)
Nsdhl	NP_035071.3	3b-HSD-NSDHL-like_SDR_e	29..355	CDD:187673	36/166 (22%)
		3Beta_HSD	31..281	CDD:279420	36/164 (22%)
		Prevents secretion from ER. /evidence=ECO:0000269\|PubMed:14506130	359..362
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910