Protein Alignment Snap24 and SNAP25

DIOPT Version :10

• Sequence 1: NP_524298.1
• Gene: Snap24 / 41193
• FlyBaseID: FBgn0266720
• Length: 212
• Species: Drosophila melanogaster
• Sequence 2: NP_003072.2
• Gene: SNAP25 / 6616
• HGNCID: 11132
• Length: 206
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 120/208 - (57%)
• Similarity: 160/208 - (76%)
• Gaps: 5/208 - (2%)

  Fly     5 ENAEPRTELQELQFKSGQVADESLESTRRMLALMDESKEAGIRTLVALDDQGEQLDRIEEGMDRI 69
            |:|:.|.||:|:|.::.|:||||||||||||.|::|||:|||||||.||:|||||||:||||:.|
Human     3 EDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHI 67

  Fly    70 NADMREAEKNLSGMEKCCGICVLPWKKVNIKDDGESAWKANDDGKIVASQPQRVIDERERGGMGA 134
            |.||:||||||..:.||||:.:.|..|:...|..:.||..|.|| :|||||.||:||||:..:
Human    68 NQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDG-VVASQPARVVDEREQMAI-- 129

  Fly   135 PPQSGYVARITNDAREDEMDENLGQVNSMLGNLRNMALDMGSELENQNKQVDRINAKGDANNIRM 199
              ..|::.|:||||||:||||||.||:.::||||:||||||:|::.||:|:|||..|.|:|..|:
Human   130 --SGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRI 192

  Fly   200 DGVNKRANNLLKS 212
            |..|:||..:|.|
Human   193 DEANQRATKMLGS 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snap24	NP_524298.1	SNARE_SNAP25N_23N	18..82	CDD:277242	47/63 (75%)
		SNAP-25	93..149	CDD:459955	24/55 (44%)
		SNARE_SNAP25C	150..208	CDD:277238	34/57 (60%)
SNAP25	NP_003072.2	SNARE_SNAP25N	10..82	CDD:277247	51/71 (72%)
		SNAP-25	91..142	CDD:459955	24/55 (44%)
		SNARE_SNAP25C	143..201	CDD:277238	34/57 (60%)