Protein Alignment FoxP and Foxp4

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_017173175.1
• Gene: Foxp4 / 74123
• MGIID: 1921373
• Length: 692
• Species: Mus musculus
• Alignment Length: 371
• Identity: 162/371 - (43%)
• Similarity: 201/371 - (54%)
• Gaps: 68/371 - (18%)

  Fly   155 HPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQA 219
            |||:.||.|:|||||...||:..|:|||||||.||||||||.|||||||.|||..|.||.:||||
Mouse   307 HPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQA 371

  Fly   220 MMHHLYLS-------KQLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRPIRQTNSP-------SP 270
            ||.||::.       .|...|.......||| ...|  |.:||::...|....:.|       :|
Mouse   372 MMAHLHMRPSEPKPFSQPHLPHCSQLNPVPG-SSSF--SKVTVSADPFPDGLVHPPTSAAAPVTP 433

  Fly   271 LNLPMVNSTNLCS---IKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFT 332
            |..|.:.|.:|.|   .::|::||....|:               .|:.:|.|||||||||||||
Mouse   434 LRPPGLGSASLHSGGPARRRSNDKFCSPIS---------------SELAQNHEFYKNADVRPPFT 483

  Fly   333 YASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFW 397
            |||||||||:::||:|||||||||||...|.|||||.||||||:|.||||||||||.|:..|:.|
Mouse   484 YASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVW 548

  Fly   398 MVDDNEFVKRRHLSRGRPRKYEPS-----------------SSPNSCQSGNGVPTDKNPCDNCTQ 445
            .||:.|:.||      ||.|...|                 :|..:..:.:..|...||
Mouse   549 TVDEREYQKR------RPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLSNP------ 601

  Fly   446 HCTSLPPGADNPLDSNNPNDLGRIG-CLPYCGSDGLSKAS-KDYSN 489
              ..|.||:.:.|...:..|||..| .||..||....:.| ..||:
Mouse   602 --GMLNPGSASSLLPLSQEDLGVPGEPLPSNGSSSPPRLSPPQYSH 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036	46/66 (70%)
		FH_FOX	327..408	CDD:469596	58/80 (73%)
Foxp4	XP_017173175.1	FOXP-CC	309..376	CDD:465036	46/66 (70%)
		COG5025	<375..>572	CDD:227358	95/220 (43%)
		FH_FOXP4	479..565	CDD:410841	61/91 (67%)