DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FoxP and fd102C

DIOPT Version :9

Sequence 1:	NP_001247011.1	Gene:	FoxP / 41182	FlyBaseID:	FBgn0262477	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	52/187 - (27%)
Similarity:	85/187 - (45%)	Gaps:	24/187 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 NGGLPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNT 361
            :|.||.:...|.|.......:.:..::..:.:|..:|..||..||:.|.|.:|.|::||.:..:.
  Fly    98 SGSLPSVNRMAALSTISLFPQTQRIFQPEEPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDN 162

  Fly   362 FCYFRRNAATWKNAIRTNLSLHKCFV---RYEDDFGSFWMV---DDNEFVK---RRHLSRGRPRK 417
            :.|||.....|:|:||.||||:.||:   |..:..|.:|.:   :..:|.|   ||..::.:.||
  Fly   163 YPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSANGKGHYWAIHPANMEDFRKGDFRRRKAQRKVRK 227

  Fly   418 YEPSSSPNSCQSGNGVPTDKNPCDNCTQHCTSLPPGADNPLDSNNPNDLGRIGCLPY 474
            :...|..::.......|    |.|..|      ||    |..|.:...|..:| .||
  Fly   228 HMGLSVDDASTDSPSPP----PLDLTT------PP----PPSSQSALQLSALG-YPY 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777
FoxP	NP_001247011.1	FH	328..400	CDD:238016	28/77 (36%)
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	29/83 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840