Protein Alignment FoxP and Foxp3

DIOPT Version :9

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_038955722.1
• Gene: Foxp3 / 317382
• RGDID: 1562112
• Length: 457
• Species: Rattus norvegicus
• Alignment Length: 336
• Identity: 113/336 - (33%)
• Similarity: 168/336 - (50%)
• Gaps: 73/336 - (21%)

  Fly   112 EFISEQEKLMFSDAERFLRS----KDNEVCNNDFSYMHDEFAMRKYYHPLFAHGICRWPGCEMDL 172
            |::|.:..|:.:    |.||    ||:.:           .|..:..:||.|:|:|:|||||...
  Rat   187 EWVSREPALLCT----FPRSGTPRKDSNL-----------LAAPQGSYPLLANGVCKWPGCEKAF 236

  Fly   173 EDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKID 237
            |:...|:||...:|.||::..||..:|.:||..||..|:.|:::|.||..||.....|.....:.
  Rat   237 EEPGEFLKHCQADHLLDEKGKAQCLLQREVVQSLEQQLELEKEKLGAMQAHLAGKMALTKAPPVA 301

  Fly   238 RKDVPGREGKFCRSPLTVNSIGRPIRQTNSPSPLNLPMVNSTNLCSIKKR---NHDKNTFSINGG 299
            ..|    :...|.  :..::.|..:...:||...      |.:|.::::.   :|..:||
  Rat   302 SVD----KSSCCL--VATSTQGSVLPAWSSPREA------SDSLFAVRRHLWGSHGNSTF----- 349

  Fly   300 LPYMLERAGLDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCY 364
                         .|...|.:::|..::|||||||:|||.||:::|::|.||||||:||...|.|
  Rat   350 -------------PEFFHNMDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMFAY 401

  Fly   365 FRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVDDNEFVKRRHLSRGRPRKYEPSSSPNSCQS 429
            ||.:.||||||||.||||||||||.|.:.|:.|.||:.||.|:|            |..|:.|
  Rat   402 FRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEFEFRKKR------------SQRPSKC-- 452

  Fly   430 GNGVPTDKNPC 440
                   .|||
  Rat   453 -------SNPC 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:292777	28/66 (42%)
		FH	328..400	CDD:238016	47/71 (66%)
Foxp3	XP_038955722.1	FOXP-CC	221..288	CDD:406546	28/66 (42%)
		FH_FOXP3	365..445	CDD:410840	52/79 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	126	1.000	Domainoid score	I5287
eggNOG	1	0.900	-	-		E2759_KOG4385
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45796
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910