Protein Alignment FoxP and Foxp2

DIOPT Version :10

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_036021645.1
• Gene: Foxp2 / 114142
• MGIID: 2148705
• Length: 740
• Species: Mus musculus
• Alignment Length: 371
• Identity: 159/371 - (42%)
• Similarity: 202/371 - (54%)
• Gaps: 75/371 - (20%)

  Fly   142 SYMHDEFAMRKYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQL 206
            |..|:|....   |.|:.||:|:|||||...||...|:||||.||.||||||||.|||||||.||
Mouse   355 SSSHEETGAS---HTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQL 416

  Fly   207 ESHLQKERDRLQAMMHHLYLSK----------QLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRP 261
            |..|.|||:||||||.||::..          .|:|...:.:..:........::|.|..:...|
Mouse   417 EIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTP 481

  Fly   262 IRQTNSPS---PLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYK 323
            |  |..||   |.::|     |:.:|::|:.||               ..:.:..||..|.||||
Mouse   482 I--TQGPSVITPASVP-----NVGAIRRRHSDK---------------YNIPMSSEIAPNYEFYK 524

  Fly   324 NADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVR 388
            |||||||||||:||||||::|.|:||||||||:||..||.||||||||||||:|.||||||||||
Mouse   525 NADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVR 589

  Fly   389 YEDDFGSFWMVDDNEFVKRRHLSRGRPRKYEPSSSPNSCQSGNGVPT-DKN-PCDNCTQHCTSLP 451
            .|:..|:.|.||:.|:.|||                  .|...|.|| .|| |        |||.
Mouse   590 VENVKGAVWTVDEVEYQKRR------------------SQKITGSPTLVKNIP--------TSLG 628

  Fly   452 PGADNPLDSNNPNDLGRIGCLPYCGSDGLSKASKDYSNMDSGMIES 497
            .||  .|:::....|.. ..||...:.||      .:|..||::::
Mouse   629 YGA--ALNASLQAALAE-SSLPLLSNPGL------INNASSGLLQA 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036	46/66 (70%)
		FH_FOX	327..408	CDD:469596	58/80 (73%)
Foxp2	XP_036021645.1	FOXP-CC	367..434	CDD:465036	46/66 (70%)
		COG5025	502..>733	CDD:227358	94/214 (44%)
		FH_FOXP2	528..609	CDD:410839	58/80 (73%)