Protein Alignment FoxP and foxp2

DIOPT Version :9

• Sequence 1: NP_001247011.1
• Gene: FoxP / 41182
• FlyBaseID: FBgn0262477
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_012813833.2
• Gene: foxp2 / 100101742
• XenbaseID: XB-GENE-482683
• Length: 744
• Species: Xenopus tropicalis
• Alignment Length: 365
• Identity: 155/365 - (42%)
• Similarity: 197/365 - (53%)
• Gaps: 63/365 - (17%)

  Fly   142 SYMHDEFAMRKYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQL 206
            |..|:|....   |.|:.||:|:|||||...||...|:||||.||.||||||||.|||||||.||
 Frog   329 SSSHEETGAS---HTLYGHGVCKWPGCENICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQL 390

  Fly   207 ESHLQKERDRLQAMMHHLYLSK----------QLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRP 261
            |..|.|||:||||||.||::..          .|:|...:.:..:........::|.|..:...|
 Frog   391 EIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSTVTMSKNMLETSPQSLPQTPTTPTAPVTP 455

  Fly   262 IRQTNSPS---PLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAGLDVQQEIHRNREFYK 323
            |.|  .||   |.::|     |:.:|::|:.||               ..:.:..||..|.||||
 Frog   456 IAQ--GPSVITPASVP-----NVGAIRRRHSDK---------------YNIPMSTEIAPNYEFYK 498

  Fly   324 NADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVR 388
            |||||||||||:||||||::|.|:||||||||:||..||.||||||||||||:|.||||||||||
 Frog   499 NADVRPPFTYATLIRQAIMESGDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVR 563

  Fly   389 YEDDFGSFWMVDDNEFVKRRHLS-RGRPR--KYEPSS---------SPNSCQSGNGVPTDKNPCD 441
            .|:..|:.|.||:.|:.|||... .|.|.  |..|:|         |..:..:.:.:|...|
 Frog   564 VENVKGAVWTVDEAEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSN--- 625

  Fly   442 NCTQHCTSLPPG--------ADNPLDSNNPNDLGRIGCLP 473
              |....:..||        .:..||..:.|.....||.|
 Frog   626 --TGLLNNASPGLLQAVHEDLNGSLDHIDSNGNSSPGCSP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FoxP	NP_001247011.1	FOXP-CC	157..224	CDD:465036	46/66 (70%)
		FH_FOX	327..408	CDD:469596	58/80 (73%)
foxp2	XP_012813833.2	FOXP-CC	341..408	CDD:465036	46/66 (70%)
		COG5025	476..>668	CDD:227358	90/208 (43%)
		FH_FOXP2	502..583	CDD:410839	58/80 (73%)