Protein Alignment phu and Akp3

DIOPT Version :10

• Sequence 1: NP_649897.4
• Gene: phu / 41135
• FlyBaseID: FBgn0043791
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_073171.2
• Gene: Akp3 / 64621
• RGDID: 621650
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 206/500 - (41%)
• Similarity: 282/500 - (56%)
• Gaps: 38/500 - (7%)

  Fly    53 QIVFDAVRSEERYAEYWQGLAAQTLDQQLESKLRLNTQLARNVMLFIGDGMSIPTITAGRVYLG- 116
            |:....:..||....:|...||..|:  :..||:.....|:|:::|:||||.:||:||.|:..|
  Rat    15 QLSLSVIPVEEENPAFWNQKAADALN--VAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQ 77

  Fly   117 -----GEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQA 176
                 |.|...|.:.|||:.|||||..:.||.|||.||||||.|||.||.|||||||.:|..|
  Rat    78 LEGNLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQC-- 140

  Fly   177 QAQAAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGDPDLCPD 241
            .....:.|.|:...|:|.|.:.|:||||.|.||||||.|.|..||||..||::.. :...:.|.|
  Rat   141 NTTFGNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPA-SALQEGCKD 204

  Fly   242 AAAQLINSPVGQKLNVIMGGGRENFLPKGVTDSS-----GAPGRRLDGRNLIDEWKNQHTNSAQY 301
            .|.||:::   ..:|||:||||:...|.|..|..     ...|.||||:||:.||.::|..| ||
  Rat   205 IATQLVSN---MDINVILGGGRKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLSKHQGS-QY 265

  Fly   302 VENRRELL--NLSNHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYFLF 364
            |.||:||:  :|....:.::|||.|....:.:...|...|:|::|.::|:.:|.|..  :|::||
  Rat   266 VWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNP--KGFYLF 328

  Fly   365 VEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDI 429
            |||||||.|||...|..|:.|...||.|:..|...||..|||.:|::||||..|..||:.|...|
  Rat   329 VEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSI 393

  Fly   430 FG---INDGQLAADDLPYATLSYANGPGYDSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLES 491
            ||   :|    |.|..||.::.|.|||||       .|...|.|:......:..:...:.||::|
  Rat   394 FGLAPLN----ALDGKPYTSILYGNGPGY-------VGTGERPNVTDAESHDPSYQQQAAVPVKS 447

  Fly   492 ETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRNMC 536
            |||||:|||:||.||.|.|..||.||::|.|.:.:|.||.....|
  Rat   448 ETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDC 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	alkPPc	93..530	CDD:214515	193/452 (43%)
Akp3	NP_073171.2	Alk_phosphatase	52..486	CDD:395188	194/453 (43%)