Protein Alignment phu and Alpl

DIOPT Version :10

• Sequence 1: NP_649897.4
• Gene: phu / 41135
• FlyBaseID: FBgn0043791
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_037191.2
• Gene: Alpl / 25586
• RGDID: 2100
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 221/509 - (43%)
• Similarity: 304/509 - (59%)
• Gaps: 43/509 - (8%)

  Fly    59 VRSEERYAEYWQGLAAQTLDQQLESKLRLNTQLARNVMLFIGDGMSIPTITAGRVYLG------G 117
            |..:|:...||:..|.:||...|:.: :|||.:|:|:::|:||||.:.|:||.|:..|      |
  Rat    19 VPEKEKDPSYWRQQAQETLKNALKLQ-KLNTNVAKNIIMFLGDGMGVSTVTAARILKGQLHHNTG 82

  Fly   118 EEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQAQAQAAH 182
            ||.:...::||:|.|||||..|.||.|||.||||||.|||||.||:|||||.:...|  .....:
  Rat    83 EETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRC--NTTQGN 145

  Fly   183 HVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGDPDL----CPDAA 243
            .|:||..||:..|.:.|:||||.|.||:|:..|||.|:|:|.:|.|:     .|:.    |.|.|
  Rat   146 EVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEM-----PPEALSQGCKDIA 205

  Fly   244 AQLINSPVGQKLNVIMGGGRENFLPKGVTD-----SSGAPGRRLDGRNLIDEWKN---QHTNSAQ 300
            .||:::.  :.::|||||||:...||..||     ...|.|.||||.:||..||:   :|.:| .
  Rat   206 YQLMHNI--KDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHS-H 267

  Fly   301 YVENRRELLNLSNHTSRV---LGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYF 362
            ||.||.|||.|.  .|||   ||||.|..|.|.|:.:....|:|.|||:.|:.||.:..  :|:|
  Rat   268 YVWNRTELLALD--PSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNP--KGFF 328

  Fly   363 LFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKN 427
            |.|||||||||||:..|.:|:.|..|.|:|:..|.:.||..|||.||::||||..:..||:.|.|
  Rat   329 LLVEGGRIDHGHHEGKAKQALHEAVEMDEAIGKAGTMTSQKDTLTVVTADHSHVFTFGGYTPRGN 393

  Fly   428 DIFGINDGQLAADDLPYATLSYANGPGYDSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLESE 492
            .|||:.......|..|:..:.|.|||||.   :.:|   .|:|:..::..:.::...|.|||..|
  Rat   394 SIFGLAPMVSDTDKKPFTAILYGNGPGYK---VVDG---ERENVSMVDYAHNNYQAQSAVPLRHE 452

  Fly   493 THGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCL-SDRNMCVDGGVARRP 545
            ||||:||||||.||.|.|..||.||::|||.:.||||: ::.:.|.....|..|
  Rat   453 THGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWASSASSP 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	alkPPc	93..530	CDD:214515	205/457 (45%)
Alpl	NP_037191.2	Alk_phosphatase	51..490	CDD:395188	206/458 (45%)