Protein Alignment phu and alpi.2

DIOPT Version :10

• Sequence 1: NP_649897.4
• Gene: phu / 41135
• FlyBaseID: FBgn0043791
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001116946.1
• Gene: alpi.2 / 100144722
• XenbaseID: XB-GENE-854953
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 215/499 - (43%)
• Similarity: 289/499 - (57%)
• Gaps: 48/499 - (9%)

  Fly    63 ERYAEYWQGLAAQTLDQQLESKLRLN--TQLARNVMLFIGDGMSIPTITAGRVYLG------GEE 119
            |:..::|...|.:|    |::.|.||  |..|:|:::|:||||.:.||.|.|:|.|      |||
 Frog    39 EKNPKFWNDQAKET----LKNALNLNPITHRAKNLIMFLGDGMGVTTIAAARIYQGQVEGQPGEE 99

  Fly   120 KQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQAQAQAAHHV 184
            ...|.|:||||.|||.|..:.||.|||.|.||||.|||||.||:|||||..:.:|  .:...:.|
 Frog   100 NIMAMEKFPYVALSKVYNVDAQVPDSAGTGTAYLCGVKANSGTLGVSAAAIYGNC--VSSKGNEV 162

  Fly   185 SSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVG---DNGDPDLCPDAAAQL 246
            :||...|:..|.:.|:||||.|.||||...|||.|:|||.:|.|:..   :||    |.|.|.||
 Frog   163 TSILHRAKLAGKSVGIVTTTRVQHASPGAAYAHSASRNWYSDNEMTSAMINNG----CKDIAYQL 223

  Fly   247 INSPVGQKLNVIMGGGRENFLPKGVTD-----SSGAPGRRLDGRNLIDEWKNQHTNSAQYVENRR 306
            :::   ..::||:||||....|.|..|     ||...|.|.||.||.|.|.::..| |:||.| :
 Frog   224 VHN---TDIDVILGGGRAYMYPAGTPDPEYPGSSADRGLRRDGLNLTDIWLSKRQN-ARYVWN-K 283

  Fly   307 ELLNLSN--HTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYFLFVEGGR 369
            |..|..|  .|..::|||.|..|.|.|:.:.:..|:|.||.:.|:.||.:..  :|:||||||||
 Frog   284 EQFNAVNVDTTDYLMGLFEPKDMKYELNRNASLDPSLAEMTEKAIRILSKNP--KGFFLFVEGGR 346

  Fly   370 IDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDIFGIND 434
            |||||||..|.:::.|..||||||......|..::||.||::||||..:..||:.|.|.|||:..
 Frog   347 IDHGHHDGNAKQSLTEALEFDKAVLRGGQLTQENETLTVVTADHSHVFTFGGYTDRGNSIFGLAP 411

  Fly   435 GQLAADDLPYATLSYANGPGY---DSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLESETHGG 496
             .||:|..||.:|.|.|||||   |:         .|.|:..:|..:..::..:.||:.||||||
 Frog   412 -SLASDRKPYTSLLYGNGPGYPLPDA---------IRANITGVNTGSNSYLQQAAVPVVSETHGG 466

  Fly   497 DDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRNMCVDGG 540
            :|||:.|.||.|.||.|..||.:|.|.:.||:||.....|...|
 Frog   467 EDVAIMAKGPQAHLFHGFHEQSYIAHVMAYAACLEPYTECPPNG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phu	NP_649897.4	alkPPc	93..530	CDD:214515	201/455 (44%)
alpi.2	NP_001116946.1	Alk_phosphatase	66..500	CDD:395188	202/456 (44%)