Protein Alignment: alpha-Man-IIa and AMS1

• Sequence 1: NP_001262413.1
• Gene: alpha-Man-IIa
• FlyBaseID: FBgn0011740
• Length: 1109
• Species: Drosophila melanogaster
• Sequence 2: NP_011359.1
• Gene: AMS1
• SGDID: S000003124
• Length: 1083
• Species: Saccharomyces cerevisiae
• Alignment Length: 902
• Identity: 189/903 (21%)
• Similarity: 318/903 (35%)
• Gaps: 219/903 (24%)

  Fly    94 QCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPG 158
            :|::::|         .|.:|  ||.: ...|::||          .:.....|:.:.:.|.|..
Yeast   260 KCRELLQ---------REYFD--SFLE-SSKVYEQG----------ESQVLTNVYGIGNCHIDTA 302

  Fly   159 WIQTFEEYYQHDTKHILSNALRHLHDN-PEMKFIWAEISYFARFYHDLGE--NKKLQMKSIVKNG 220
            |:..|.|..:...:...|...  |.|. ||.||:.::...|.....|..|  ||.|..|  ::..
Yeast   303 WLWPFAETRRKIVRSWSSQCT--LMDRFPEYKFVASQAQQFKWLLEDHPEFFNKVLIPK--IQQS 363

  Fly   221 QLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGF 285
            |...|.|.||..|.......::..|...||.:..:...:.....|..|.||:|..||.:.:.||.
Yeast   364 QFFAVGGTWVENDTNIPSGESLARQFFFGQRFFLKHFGLKSKIFWLPDTFGYSSQMPQLCRLSGI 428

  Fly   286 KNMLIQRTHYSVKKELAQQRQLEFLWRQI---------WDNKGDTALFTHMMPFYSYDIPHTCGP 341
            ...|.|:                ..|..|         |.....:.|.|||.|..:|......|
Yeast   429 DKFLTQK----------------LSWNNINSFPHSTFNWAGIDGSQLLTHMPPGNTYTADSHFG- 476

  Fly   342 DPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDF 406
                    |..|                .:.||             |..|.|.:.::|...||.
Yeast   477 --------DVLR----------------TAKQN-------------KTPEYYGSGLMLYGKGDG- 503

  Fly   407 RFKQNTEWDVQRVNYERLFEHINSQAHFNV--QAQFG-TLQEYFDAVHQAERAGQAEFPTLSGDF 468
             ....||..:|::...|...:.|.    ||  :.|.| |:.|::|.:.:....|. :.||.||:.
Yeast   504 -GGGPTEEMLQKMRRIRSMNNRNG----NVIPKLQVGITVDEFYDDILKRTNQGH-DLPTWSGEL 562

  Fly   469 FTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSW---DGMARIEERLEQARRELS 530
            :.      .:..|.|||:...|::.|:....:...|.::|..|.   |......:::.:....:.
Yeast   563 YF------EFHRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDSYKYPSKQINELWENVL 621

  Fly   531 LFQHHDGITGTAKTHVVVDYE--QRMQEALKACQMVMQQSV-------------YRLLT--KPSI 578
            |.|.||.:.|:. ..:|..||  ..:...:|.|..::.::|             .|.||  ||..
Yeast   622 LCQFHDVLPGSC-IEMVYKYEAVPMLHNVVKECTSLIDKTVQFLQSQSKADLVEMRTLTWSKPEK 685

  Fly   579 YSPDFSFS------------YFTLDDSR-----WPGSGVEDSRTTIILGEDILPSKH-------- 618
            .|.:.|.:            |..|.:.:     ...:||..|.|...||.:.|.::|
Yeast   686 VSEECSLNGSYTSSVTGYDDYIVLANGKLKVIICKKTGVITSITDETLGVEYLDTEHGRNKLGAN 750

  Fly   619 -VVMHNTLP----HWREQLVDF----YVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQ 674
             .|:::..|    .|..:|...    ||:.| ..|....|...:..|..::........|::...
Yeast   751 QFVIYDDKPLGWQAWDTELYSVNQYKYVTKP-KKVQVSCNTKEKCAVEVIFQISEKCKIKSVISL 814

  Fly   675 GSTTKYRIIFKARVPPMGLATYV---------LTIS---DSKPEHTSYASNLLLRKNP----TSL 723
            .:|.    :..|::..:.::|.|         |.:.   :.:.:..||.:...:.|.|    ||.
Yeast   815 NATA----VTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDFASYETQFGITKRPTHYNTSW 875

  Fly   724 PLGQYPEDV---KFGDPREISLRVG--NGPTLAFSEQGLLKSIQLTQDSPHVP-VHFKF----LK 778
            .:.::  :|   ||.|..|.|..|.  |.....||..|.|..:.|.: ||..| .|...    :|
Yeast   876 DVAKF--EVCHHKFADYSEYSKGVSILNDCKYGFSTHGNLMRLSLLR-SPKAPDAHADMGTHEIK 937

  Fly   779 YGVRSHGDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSV---------GLPSVVHQTIMR 834
            |.:..|   .||.      .:..|:|........|.||...:.:         |..:|:...|.|
Yeast   938 YAIYPH---RGAL------SSDTVKLAHEFNYCFKYKLPKDIGMNFDDIISISGDENVILSNIKR 993

  Fly   835 G-GAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKR-RRLDKLPLQ 889
            | ....:::...:...|...||:|:...:  |...:..||....:|| .::|.|.::
Yeast   994 GEDDSAVKSNYSLNPRDEQSIVVRVYESL--GGESFASLNTTLNLKRIEKVDNLEMK 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIa	NP_001262413.1	GH38N_AMII_GMII_SfManIII_like	144..483	CDD:212120	78/354 (22%)
		Alpha-mann_mid	478..554	CDD:214875	18/81 (22%)
		Glyco_hydro_38C	744..1103	CDD:285047	37/165 (22%)
AMS1	NP_011359.1	AMS1	44..1083	CDD:223460	189/903 (21%)
		GH38N_AMII_ScAms1_like	290..548	CDD:212123	72/322 (22%)
		Alpha-mann_mid	565..646	CDD:286360	18/82 (22%)
		Glyco_hydro_38C	672..1079	CDD:285047	82/397 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C65919859
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3970
TreeFam	0	0.000	Not matched by this tool.
	2	1.960