Protein Alignment alpha-Man-IIa and aman-1

DIOPT Version :10

• Sequence 1: NP_001262413.1
• Gene: alpha-Man-IIa / 41126
• FlyBaseID: FBgn0011740
• Length: 1109
• Species: Drosophila melanogaster
• Sequence 2: NP_508811.1
• Gene: aman-1 / 180749
• WormBaseID: WBGene00018877
• Length: 955
• Species: Caenorhabditis elegans
• Alignment Length: 955
• Identity: 262/955 - (27%)
• Similarity: 396/955 - (41%)
• Gaps: 232/955 - (24%)

  Fly   130 WN----IKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYY--------QHDTKHILSNALRHL 182
            ||    :..||....||      ::||:|:|.|||:|.::|:        ....::|.:..:..|
 Worm    23 WNTCHKVDQDPNVITAH------LIPHTHDDLGWIKTVDQYFWGAKPELVPVGVQYIYNTVIDEL 81

  Fly   183 HDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLT 247
            ..||:.:|.:||..:..|:|....:..:.|::.:|||||:|.:.||||..|||.||:.:::.|:|
 Worm    82 LKNPDRRFSFAETGFLWRWYTSNSDFDRHQLQKLVKNGQIEIIGGGWVQNDEATSHYVDIIDQMT 146

  Fly   248 EGQTWLKQFMNV--TPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFL 310
            .|...|:|....  .|...|.|||||||..|..|.::.|:.::...|.||..|:...:.:.|||:
 Worm   147 LGLQRLEQIFGECGKPVTGWQIDPFGHSREMANIYREMGYSSVYFARIHYLEKQIRLKNKTLEFM 211

  Fly   311 WR---QIWDNKGDTALFTHMMPFYSYDIPH------TCGPDPKVCCQFDFKRMGSFGLSCPWKVP 366
            |.   .|.|||    |||......:|..|.      .||.||                    .:.
 Worm   212 WNTSDDITDNK----LFTGAFFNDNYGPPEGFCWDSLCGDDP--------------------IMD 252

  Fly   367 PRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQ 431
            ...|...||..:.|..||..|.:|....||.:::.:|.||::.....|   .||.::|.:::|:.
 Worm   253 NLNIEGYNVKEKVDAFVDHVKNQAAHQSTNQVMLLMGSDFQYTNANSW---YVNLDKLIKYVNAD 314

  Fly   432 AHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLS---GDFFTYADRSDNYWSGYYTSRPYHKRMD 493
            ....|:..:.|...|..||       ||:.||||   .|||.||....:||:||:||||..|.|.
 Worm   315 TSKKVRVIYSTPACYTKAV-------QAKTPTLSVKHDDFFPYASGRHSYWTGYFTSRPAFKGMI 372

  Fly   494 RVLMHYVRAAEMLSAWHSWDGMARI----EERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRM 554
            |      :|:.||......|.:|.:    :..:|..|...:|.||||.:|||||.:|..|||:::
 Worm   373 R------QASCMLQLAKQLDVIANLGPEDDSDIEILREASALVQHHDAVTGTAKENVTRDYEKQL 431

  Fly   555 QEALKACQMVMQQSVYRL------------------LTKPSIYSPDFSFSYFTLDDSRWPGS-GV 600
            .:.:...::|:...:.::                  :.||...|.:||...|..:...:.|: .:
 Worm   432 AKGVSEVEVVINDFMKKMNPDGLDPKLVLCPLINETICKPINGSSEFSVVIFNSNGRYFNGTIRI 496

  Fly   601 EDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHD 665
            ..|:.|.:|                                   .|...|.:|:|:  |.::..|
 Worm   497 PYSQKTAVL-----------------------------------RDAHKNVLESQI--VETFQID 524

  Fly   666 TLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLLRKNPTSLPLGQYPE 730
            .|..|     ....|.|....||||:|..| |.....||||...:.:    ||
 Worm   525 QLKDT-----DRLPYEIHVFVRVPPLGYTT-VFVEKGSKPERVHFNN----RK------------ 567

  Fly   731 DVKFGDPREISLRVGNGPTLA-FSEQGLLKSIQLTQDSPHVPVHFKFLKY-GVRSHGDR-SGAYL 792
              ||....||.    |...:| |..||.|..|..........:..:|..| |:.|..|: ||||:
 Worm   568 --KFNTNVEIQ----NEYLIAGFDSQGYLSYITEKATKKKRSIRQEFFYYEGIDSKDDQPSGAYI 626

  Fly   793 FLPNGPASPVELGQPVVLVTK-------GKLESSVSVGLPSVVHQTIMRGGAPEIRNLVD----I 846
            |.|       :..||:.|.:|       |.:.:.|...:...|.|.|.   .|..:|.::    :
 Worm   627 FRP-------KTQQPIALTSKLALEVVPGAIINEVRQKVSPFVSQQIR---LPRGKNYIEFEWIV 681

  Fly   847 GSLD-------NTEIVMRLETHIDSGDIFYTDLNGLQFIKR--------RRLDKLPLQANYYPIP 896
            |.:.       ..|.|.|..|.:.|.:..:||.||.|.::|        ...|..|:..|||||.
 Worm   682 GPIPKETKNPITKEFVTRYTTEVHSKNQSFTDSNGRQAMERFFDGATSFEYSDTEPIAGNYYPIT 746

  Fly   897 SGMFIEDANTRLTLLTGQPLGGSSLAS-GELEIMQDRRLASDDERGLGQGVLDNKPVLHIYRLVL 960
            |..:|:|.|.:.:::|.:..|  .:|| |.:|||..||...||..|: :..||
 Worm   747 SFGYIKDENAQFSVITDRAQG--MVASDGVVEIMLHRRCFYDDHFGV-EEALD------------ 796

  Fly   961 EKVNNCVRPSELHPAGYLTSAAH-------KASQSLLDPL--DKF 996
                   .|.: ..||.:....|       |||.|.|.||  |.|
 Worm   797 -------EPGK-DGAGLVAMGKHIVLFTDVKASTSQLRPLAIDNF 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-IIa	NP_001262413.1	PLN02701	105..990	CDD:178304	257/945 (27%)
		Glyc_hyd_38C_2	1020..1108	CDD:408054
aman-1	NP_508811.1	PLN02701	23..871	CDD:178304	262/955 (27%)
		GH38N_AMII_LAM_like	36..313	CDD:212121	91/309 (29%)