DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aduk and stk35

DIOPT Version :9

Sequence 1:	NP_731331.1	Gene:	Aduk / 41112	FlyBaseID:	FBgn0037679	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001071084.1	Gene:	stk35 / 568080	ZFINID:	ZDB-GENE-061103-553	Length:	406	Species:	Danio rerio

Alignment Length:	369	Identity:	87/369 - (23%)
Similarity:	150/369 - (40%)	Gaps:	116/369 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PRITDFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLREL--KHK 66
            ||   :.::.::|.|||..||:|..::.....|||.:......:.  |..:.|...|..|  :|:
Zfish    69 PR---YSLIREVGRGSYGVVYEAVARRSGARVAIKKLRCDAPEKV--ELALAEFWALASLEKRHE 128

  Fly    67 YIVTLQD-------------------------------------------FFWDDKNIYIVLEYC 88
            .:|.|::                                           :.|      .|:|:|
Zfish   129 NVVQLEECVLQRNGMAQKMSHGNKRNKQYLRLVETSLKGERILGYPEEPCYLW------FVMEFC 187

  Fly    89 NAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDLKPQNLLLTRGANNVSLKVADF 153
            :.|:|:.:|.:::..|. |.|.|::||.:||.::..|::.|.||||.|:|:::.:.|..:|||||
Zfish   188 DGGDLNQYILSRRPDPR-TNRSFMKQLTSAVAFLHKNNIVHRDLKPDNILISQKSGNPVIKVADF 251

  Fly   154 GFAQ-----------------HLKLGEINQ----QLKGSPLYMAPEIVRKHQYDAKADLWSIGVI 197
            |.::                 :..:..||:    ...||..|||||:...| |.||||::::|:|
Zfish   252 GLSKVCAGLSCMQNEGDDQVNNKNIVNINKFWLSSACGSDFYMAPEVWEGH-YTAKADIFALGII 315

  Fly   198 LYECLFGKAPYSSRTIEELL-LRIRKAEAIT---------------LPPNAR--ISNECHDLLRR 244
            ::..:.......:.:..||| ..:|:...|.               :|...|  :|.....||:.
Zfish   316 IWAMIERITFIDAESKRELLGTYVRQGTEIVPVGEALLENPKMVLHIPQKTRSIMSEGVKRLLQD 380

  Fly   245 LLAHEPTARISFADFFAHPFLDLKTFPTEHTLQKAIDLVTQACA 288
            :||..|..|                 |....|:..:|.||  ||
Zfish   381 MLAVNPQDR-----------------PDAFQLEVRMDQVT--CA 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	S_TKc	9..265	CDD:214567	78/339 (23%)
		PKc_like	13..264	CDD:304357	78/334 (23%)
		MIT_2	274..348	CDD:239147	6/15 (40%)
		MIT	407..472	CDD:282117
stk35	NP_001071084.1	PKc_like	70..401	CDD:304357	81/360 (23%)
stk35	NP_001071084.1	S_TKc	71..395	CDD:214567	79/350 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0595
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900