Protein Alignment Aduk and Ulk2

DIOPT Version :10

• Sequence 1: NP_731331.1
• Gene: Aduk / 41112
• FlyBaseID: FBgn0037679
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_006533571.1
• Gene: Ulk2 / 29869
• MGIID: 1352758
• Length: 1051
• Species: Mus musculus
• Alignment Length: 270
• Identity: 106/270 - (39%)
• Similarity: 168/270 - (62%)
• Gaps: 10/270 - (3%)

  Fly     6 ITDFEILEK--LGAGSYATVYKARHKKQRTYH-AIKYVEMSTLSQTSRENLITEIRLLRELKHKY 67
            :.|||..::  :|.|::|.|::.||:::..:. |||.:....||: |:..|..||::|:||:|:.
Mouse     4 VGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSK-SQILLGKEIKILKELQHEN 67

  Fly    68 IVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDL 132
            ||.|.|......::::|:||||.|:|:.:::.|..|.|.|.|.||.|:|||::.:.:..:.|.||
Mouse    68 IVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 132

  Fly   133 KPQNLLLT---RGANNVS---LKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADL 191
            ||||:||:   |..:|||   :|:||||||::|....:...|.|||:|||||::....|||||||
Mouse   133 KPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADL 197

  Fly   192 WSIGVILYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISF 256
            ||||.::|:||.||.|:.:.:.::|.:...|..::........|....:||..||......|:.|
Mouse   198 WSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDF 262

  Fly   257 ADFFAHPFLD 266
            ..||:||||:
Mouse   263 EAFFSHPFLE 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	Protein Kinases, catalytic domain	13..264	CDD:473864	100/259 (39%)
		MIT_2	274..348	CDD:239147
		MIT	410..472	CDD:461228
Ulk2	XP_006533571.1	STKc_ULK2	2..272	CDD:271103	105/268 (39%)
		DUF3543	<865..1019	CDD:463451