Protein Alignment Aduk and ulk3

DIOPT Version :10

• Sequence 1: NP_731331.1
• Gene: Aduk / 41112
• FlyBaseID: FBgn0037679
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001082941.1
• Gene: ulk3 / 100037316
• ZFINID: ZDB-GENE-070410-33
• Length: 468
• Species: Danio rerio
• Alignment Length: 499
• Identity: 194/499 - (38%)
• Similarity: 288/499 - (57%)
• Gaps: 52/499 - (10%)

  Fly     4 PRITDFEILEKLGAGSYATVYKA-RHKKQRTYHAIKYVEMSTLSQTSRENLITEIRLLRELKHKY 67
            |::.||.:.|:||:|:||||||| |....|...|:|.|...:|:::|.|||:|||.:|:.::|.:
Zfish     9 PKLKDFILTERLGSGTYATVYKAFRKTDSREAVAVKVVSKKSLNKSSMENLLTEIEILKTVRHPH 73

  Fly    68 IVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKALPESTCRYFLRQLAAAVQYMRANDVSHFDL 132
            ||.|:||.||.:|||::||:|:.|:||.|||:::.|||...|..|:|:|.|:|::...::||.||
Zfish    74 IVQLKDFQWDSENIYLILEWCSGGDLSRFIRSRRILPERVARRCLQQIACALQFLHERNISHLDL 138

  Fly   133 KPQNLLLTRGANNVSLKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIGVI 197
            ||||:||   :.|: ||::||||||::...:....|:|||||||||||.:..|||:.||||:|||
Zfish   139 KPQNILL---SGNM-LKLSDFGFAQYMSPWDEQHALRGSPLYMAPEIVCRKHYDARVDLWSVGVI 199

  Fly   198 LYECLFGKAPYSSRTIEELLLRIRKAEAITLPPNARISNECHDLLRRLLAHEPTARISFADFFAH 262
            |||.|||:||::||:..||..:||....:.||..|.:|.:|.|||.|||..:|..||.|.:||.|
Zfish   200 LYEALFGRAPFASRSFTELEEKIRSERPVELPAAAGVSRDCRDLLLRLLLRDPDRRICFEEFFLH 264

  Fly   263 PFLDLKTFPTEHTLQKAIDLVTQACAYDEKHNYKEAYYLYCSALQYFVPLITEETDATKRLALRN 327
            ||:||:..|:..:|.||..||.||...|:..:...|..||||||:.|||.|..|||..::.|||.
Zfish   265 PFVDLEHMPSAESLPKAKALVLQAVQKDQDGDRSAALSLYCSALEQFVPAIHYETDRQRKEALRQ 329

  Fly   328 RALSYTKRAEEIKNCIIEDEYRMLAERQRQAATAATANQEPSSATQVPAAQPSSSRVAEMLEPDS 392
            :...|..||||:| .::..:.::..|..|.|...
Zfish   330 KVNQYVCRAEELK-ALVRSDNKISFEEARSARNI------------------------------- 362

  Fly   393 RYKQLYALSNSSPSMKTGLEIGRKGELYLYERKLDAA-----LESYTSALGILVPFVNNEPKGER 452
                |..:|...|.:...||:....    ..|:...|     |:.|..:||.::..:..|.:|.|
Zfish   363 ----LIEMSRDQPRLLAALEVASTA----VAREESGAEDYDTLDLYQQSLGEMLLALAAEAQGRR 419

  Fly   453 RNLLLQQLEFWMKEAESIKSILSAKHLDDEE--QKLSTRTSLRT 494
            |.||..:::..|..||.:|.::..:....:|  :|.:...|:|:
Zfish   420 RELLHSEIKSLMSRAEYLKELIKMRETQTDESLKKDAAAESVRS 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aduk	NP_731331.1	Protein Kinases, catalytic domain	13..264	CDD:473864	127/251 (51%)
		MIT_2	274..348	CDD:239147	31/73 (42%)
		MIT	410..472	CDD:461228	17/66 (26%)
ulk3	NP_001082941.1	STKc_ULK3	18..266	CDD:271023	127/251 (51%)
		MIT	276..350	CDD:469712	31/74 (42%)
		MIT	371..442	CDD:469712	19/74 (26%)