Protein Alignment tgo and LOC1276339

DIOPT Version :10

• Sequence 1: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_061508161.1
• Gene: LOC1276339 / 1276339
• VectorBaseID: AGAMI1_010074
• Length: 851
• Species: Anopheles gambiae
• Alignment Length: 672
• Identity: 218/672 - (32%)
• Similarity: 321/672 - (47%)
• Gaps: 181/672 - (26%)

  Fly    13 ASRENHCEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAHMKALRGTGNTSSDGT 77
            :.::||.|||:|||:||..||||||.|:|.|.|::||.||||:|||||.|:|.:||..::.::|.
Mosquito   206 SKKQNHSEIEKRRRDKMNTYITELSAMIPMCHAMSRKLDKLTVLRMAVQHLKTIRGAVHSYTEGH 270

  Fly    78 YKPSFLTDQELKHLILEAADGFLFVVSCDSGRVIYVSDSVTPVLNYTQSDWYGTSLYEHIHPDDR 142
            |||:||:|||||.|||:||:||||||.||.||::|||:||:.:|||:|.|..|.|.::.:||.|.
Mosquito   271 YKPAFLSDQELKMLILQAAEGFLFVVGCDRGRILYVSESVSHILNYSQGDLLGQSWFDILHPKDV 335

  Fly   143 EKIREQLSTQESQNAGRILDLKSG-TVKKEGHQSSMRLSMGARRGFICRMRV-GNV-------NP 198
            .|::||||:.:.....|::|.|:. .||.:..|...||..||||.|.|||:. .||       .|
Mosquito   336 AKVKEQLSSSDLSPRERLIDAKTMLPVKTDVPQGVTRLCPGARRSFFCRMKCKANVQVKEEADQP 400

  Fly   199 ESMVSGHLN-----RLKQRNSLGPSRDGTNYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHC 258
            .|:.|  :|     |.||.||      ...|:|:.||||:|:|.|..:...   |.:.|.....|
Mosquito   401 NSVSS--VNNVCHRRKKQVNS------DKKYSVIQCTGYLKSWAPAKIGLE---ENETDGEGDSC 454

  Fly   259 ---CLVAIGRLQ------------------------------------------VTSTAAN---- 274
               ||||:||:|                                          .|.:::|
Mosquito   455 NLSCLVAVGRVQPNLSQSCSLSSNGLHTPSGANGGRSRNGSNAATGPGSGAGGGATGSSSNGNPS 519

  Fly   275 --DMSGSNNQS------------EFITRHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHPE 325
              ..:|||.:.            :||:||||||||.|||||...:||:.|.||||...|:::|.|
Mosquito   520 ATPSNGSNGKQLNRNTIPNLRNVQFISRHAMDGKFLFVDQRATLVLGFLPQELLGTSMYEYYHHE 584

  Fly   326 DQSHMKESFDQVLKQKGQMFSLLYRARAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNS------ 384
            |...:.||....|:....:.:.:||.|.|.:.:|.|:::..:|.||:|.|:||::..|:
Mosquito   585 DIPALAESHKAALQGTQCVTTSVYRLRTKETGFVRLQSEWKSFRNPWTKEIEYLIAKNNVILAEL 649

  Fly   385 -------------------SGKTMHGAPLDAAAA-----HTPEQVQQQQQQEQHVYVQ------A 419
                               :|:...|||......     ||..: :.|:....||...      |
Mosquito   650 GDGGTARAGGYGMGELGDGTGEPGSGAPGQPGVGYEFFNHTNGR-EIQRMINSHVEASKIGRQIA 713

  Fly   420 APGVDYARRELTPVGSATNDGMYQTHMLAMQAPTPQQQQQQQQRPG-SAQTTPVGYTYDT----T 479
            ...:|:.||    ||.::::          .:|.|.:...|   |. |:..:...::.|.    .
Mosquito   714 EQVLDHQRR----VGDSSSE----------SSPNPNEPTLQ---PAFSSALSEANHSNDAITSGE 761

  Fly   480 HSPYSAGG--PSPLAKIPK------SGTSPTPVAPNSWAALRPQQQQQQQQPVTEGYQYQQTSPA 536
            ||..::.|  ||.:|.:|.      :||.|                         ||.:.||:..
Mosquito   762 HSMVTSTGVSPSSMAVVPPTVTTRINGTLP-------------------------GYSHVQTNAI 801

  Fly   537 RSPS-GPTYTQLSAGNGNRQQA 557
            .||. ..:.||.|:.:||.:.|
Mosquito   802 ISPEHDVSQTQASSTDGNDEAA 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	35/60 (58%)
		PAS	90..154	CDD:214512	35/63 (56%)
		PAS_11	282..384	CDD:464214	42/113 (37%)
LOC1276339	XP_061508161.1	None