Protein Alignment tgo and Ahrr

DIOPT Version :10

• Sequence 1: NP_731308.1
• Gene: tgo / 41084
• FlyBaseID: FBgn0264075
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_033774.1
• Gene: Ahrr / 11624
• MGIID: 1333776
• Length: 701
• Species: Mus musculus
• Alignment Length: 616
• Identity: 125/616 - (20%)
• Similarity: 220/616 - (35%)
• Gaps: 199/616 - (32%)

  Fly    12 FASRENHCEIERRR--------------RNKMTAYITELSDMVPTCSALARKPDKLTILRMAVAH 62
            :|.|:....|::||              |:::...:..|:.::|....:..|.|||::||::|::
Mouse    10 YAGRKRRKPIQKRRLTMGAEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSY 74

  Fly    63 MK------ALRGTGNTSSDGTYKPSFLTDQELKH---------LILEAADGFLFVVSCDSGRVIY 112
            ::      ||:.|...|:..      |:.:|..:         |:||:.:||..|||.: |.:.|
Mouse    75 LRVKSFFQALQETCVWSAPA------LSPEEHSYRGFPVQEGRLLLESLNGFALVVSAE-GMIFY 132

  Fly   113 VSDSVTPVLNYTQSDWYGTSLYEHIHPDDREKIREQL----------------STQESQNAGRIL 161
            .|.::...|.:.|:|....::|::||.|||:....||                :..::...|::|
Mouse   133 ASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADTDNTVLGKLL 197

  Fly   162 DLKSGTVKKEGHQSSMRLSMGARRGFICRMRVGNVNPESMVS----GHLNRLKQRNSLGPSRDGT 222
            ..:.|     |.......|....|.||||:|....:....::    |.|..|..:....||  ||
Mouse   198 RAQEG-----GKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPS--GT 255

  Fly   223 NYAVVHCTGYIKNWPPTDMFPNMHMERDVDDMSSHCCLVAIGRLQVTSTAANDMSGSNNQSEFI- 286
            ...           |...:|                |:||.....||.        ...:|.|:
Mouse   256 ALP-----------PRLSLF----------------CIVAPVLPSVTE--------MKMKSTFLK 285

  Fly   287 TRHAMDGKFTFVDQRVLNILGYTPTELLGKICYDFFHPEDQSHMKESFDQVLKQKGQMFSLLYRA 351
            .:|..|...| :|.|...:.....:||..|:.|                ...|..|:....|:|.
Mouse   286 AKHRADIVVT-MDSRAKAVTSLCESELHPKLNY----------------LAGKSNGENGISLFRG 333

  Fly   352 RAKNSEYVWLRTQAYAFLNPYTDEVEYIVCTNSSGKTMHGAP--LDAAAAHTPEQVQQQQQQEQH 414
            :...|.  |.|..|                 .||...:.|.|  ||....    ...::::.::|
Mouse   334 QTDRSH--WARALA-----------------RSSCLCLRGGPDLLDPKGT----SGDREEEDQKH 375

  Fly   415 VYVQAAPGVDYARREL--------TPVGSATNDGMYQTHMLAMQAPTPQQQQQQQQRPGSAQTTP 471
            : ::.:||. :.:||:        |||           |:..:...|.|:.|:.
Mouse   376 I-LRRSPGA-WGQREMHKYSYGLETPV-----------HLRHLNWSTEQRSQES----------- 416

  Fly   472 VGYTYDTTHSPYSAGGPSPLAKIPKSGTSPTP-----VAPNSWAALRPQQQ-------QQQQQPV 524
               |...|..| |...|| ...:|.....|.|     ::.::.|:.|....       .|..:|:
Mouse   417 ---TTKLTRQP-SKNEPS-TCLVPHGSCVPYPGSQGMLSASNMASFRDSLDHPTGAYCSQMNRPL 476

  Fly   525 TEGYQYQQTSPARSPSGPTYTQLSAGN-GNR 554
            ::.:|.|        ..|:...:|.|: |:|
Mouse   477 SDIHQGQ--------VDPSTCHISQGSLGSR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tgo	NP_731308.1	bHLH-PAS_ARNT	9..74	CDD:381517	18/81 (22%)
		PAS	90..154	CDD:214512	22/88 (25%)
		PAS_11	282..384	CDD:464214	19/102 (19%)
Ahrr	NP_033774.1	bHLH-PAS_AhRR	27..86	CDD:381441	12/58 (21%)
		PAS	108..174	CDD:214512	22/66 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..432		9/38 (24%)
		Needed for transcriptional repression	555..701