Protein Alignment CG11964 and Ctnnbl1

DIOPT Version :10

• Sequence 1: NP_649847.1
• Gene: CG11964 / 41068
• FlyBaseID: FBgn0037644
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_079956.3
• Gene: Ctnnbl1 / 66642
• MGIID: 1913892
• Length: 563
• Species: Mus musculus
• Alignment Length: 592
• Identity: 328/592 - (55%)
• Similarity: 431/592 - (72%)
• Gaps: 40/592 - (6%)

  Fly     1 MDIGELLAFKPEQTPKRPHDDEDDEFDLASSHGKRGGVDEKTKRMRRIADAKESAHYVKQSGGAT 65
            ||:||||:::|.:..|||.|||::|.              ||:|.:  ...:|...|.::...|.
Mouse     1 MDVGELLSYQPNRGTKRPRDDEEEEL--------------KTRRKQ--TGPRERGRYREEEATAA 49

  Fly    66 GGSGTSAFEFDPELTEEERLNILKYV----ENEEADGDVLDEQSLKKLILVFEKRNLKNQEMRIK 126
                        |.|.:::..:|:.:    |.||.:.:.|||.|:||:||.||||:.||||:|||
Mouse    50 ------------EDTADDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIK 102

  Fly   127 FADSPEKFMDSEVELHTVIQELKGVATVPDLYPILVDLHGLHSLLELLAHQNTDIAVAVVDLLQE 191
            |.|:|||||:||::|:.:|||:..|||:||||.:||:|..:.|||.||.|.|||:::||||||||
Mouse   103 FPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELSAVQSLLGLLGHDNTDVSIAVVDLLQE 167

  Fly   192 VTDVDILGESQEGAESLIEALRKEQICALLVQNLERLNEQVKEEADGVHNTLAIVENLTEIDSEF 256
            :||:|.|.||:||||.||:||...|:.||||||||||:|.|:|||||||||||||||:.|...|.
Mouse   168 LTDIDTLHESEEGAEVLIDALVDGQVAALLVQNLERLDESVREEADGVHNTLAIVENMAEFRPEM 232

  Fly   257 VKEAAEQGLLAWLLKRLRGKSPFDPNKLYCSEILSILIQTENENRLLLGSLDGVDVLLQQLAVYK 321
            ..|||:||||.||||||:.|.|||.|||||||:|:||:|..:|||.|||.|||:|||||||:|:|
Mouse   233 CTEAAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFK 297

  Fly   322 RHDPASNEEQEYMQNLFNCLCSALMARENRDRFLSGEGLQLMNLMLREKKMSRNGSLKVLDHAMA 386
            ||:|::.||||.|:|||:.|||.||...||:|||.|||||||||||||||:||:.:||||||||.
Mouse   298 RHNPSTAEEQEMMENLFDALCSCLMLSSNRERFLKGEGLQLMNLMLREKKVSRSSALKVLDHAMI 362

  Fly   387 GQDGRDNCNKFVEILGLRTIFPLFMKTPKRNKQRLISADEHEEHVTSVIASMLRNCKGTHRQRML 451
            |.:|.|||:|||:|||||||||||||:|::.|:...:..||||||.|::||:|||.:|..|.|:|
Mouse   363 GPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLL 427

  Fly   452 AKFTENDHEKVDRLLELHLKYLAKVEAIDKEIDQQAKD-----PTIDEDEEAENNYIKRLTGGLF 511
            .||||||.||||||:|||.|||:.::..||:|:.:..|     ..||.|.|.| .|::||..|||
Mouse   428 NKFTENDSEKVDRLMELHFKYLSAMQVADKKIEGEKHDIVRRGEIIDNDMEDE-FYLRRLDAGLF 491

  Fly   512 TLQRIDYILLEV-SATGDTVKQRVLQILNLRGASMKTIRSIMREYAGNLGDG-DTDWREQEQNHI 574
            .||.|.||:.|: :|....::|||.||||:||:|:|.:|.|::|||.|:||| ..::||.||..|
Mouse   492 ILQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRETEQKRI 556

  Fly   575 LSLVDRF 581
            |:|::.|
Mouse   557 LALLENF 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11964	NP_649847.1	CTNNBL	87..553	CDD:462397	291/475 (61%)
Ctnnbl1	NP_079956.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		29/107 (27%)
		Nuclear localization signal. /evidence=ECO:0000250	16..33		10/32 (31%)
		CTNNBL	57..534	CDD:462397	291/477 (61%)
		HEAT 1	79..129		31/49 (63%)
		Nuclear export signal (NES). /evidence=ECO:0000250	130..140		6/9 (67%)
		HEAT 2	134..176		25/41 (61%)
		ARM 1	178..228		36/49 (73%)
		ARM 2	229..273		29/43 (67%)
		ARM 3	274..323		33/48 (69%)
		ARM 4	325..363		30/37 (81%)
		ARM 5	364..417		32/52 (62%)