Protein Alignment CG11964 and Ctnnbl1

DIOPT Version :9

• Sequence 1: NP_649847.1
• Gene: CG11964 / 41068
• FlyBaseID: FBgn0037644
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001020041.1
• Gene: Ctnnbl1 / 296320
• RGDID: 1563558
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 597
• Identity: 330/597 - (55%)
• Similarity: 430/597 - (72%)
• Gaps: 50/597 - (8%)

  Fly     1 MDIGELLAFKPEQTPKRPHDDEDDEFDLASSHGKRGGVDEKTKRMRRIADAKESAHYVKQSGGAT 65
            ||:||||:::|.:..|||.|||::|.              ||:|              ||:|...
  Rat     1 MDVGELLSYQPNRGTKRPRDDEEEEL--------------KTRR--------------KQTGPRE 37

  Fly    66 GG-----SGTSAFEFDPELTEEERLNILKYV----ENEEADGDVLDEQSLKKLILVFEKRNLKNQ 121
            .|     ..|:|     |..::::..:|:.:    |.||.:.:.|||.|:||:||.||||:.|||
  Rat    38 RGRYREDEATAA-----EDADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQ 97

  Fly   122 EMRIKFADSPEKFMDSEVELHTVIQELKGVATVPDLYPILVDLHGLHSLLELLAHQNTDIAVAVV 186
            |:||||.|:|||||:||::|:.:|||:..|||:||||.:||:|..:.|||.||.|.|||:::|||
  Rat    98 ELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELSAVQSLLGLLGHDNTDVSIAVV 162

  Fly   187 DLLQEVTDVDILGESQEGAESLIEALRKEQICALLVQNLERLNEQVKEEADGVHNTLAIVENLTE 251
            |||||:||:|.|.||:||||.||:||...|:.||||||||||:|.|:|||||||||||||||:.|
  Rat   163 DLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVREEADGVHNTLAIVENMAE 227

  Fly   252 IDSEFVKEAAEQGLLAWLLKRLRGKSPFDPNKLYCSEILSILIQTENENRLLLGSLDGVDVLLQQ 316
            ...|...|||:||||.||||||:.|.|||.|||||||:|:||:|..:|||.|||.|||:||||||
  Rat   228 FRPEMCTEAAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQ 292

  Fly   317 LAVYKRHDPASNEEQEYMQNLFNCLCSALMARENRDRFLSGEGLQLMNLMLREKKMSRNGSLKVL 381
            |:|:|||:|::.||||.|:|||:.|||.||...||:|||.|||||||||||||||:||:.:||||
  Rat   293 LSVFKRHNPSTAEEQEMMENLFDALCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVL 357

  Fly   382 DHAMAGQDGRDNCNKFVEILGLRTIFPLFMKTPKRNKQRLISADEHEEHVTSVIASMLRNCKGTH 446
            ||||.|.:|.|||:|||:|||||||||||||:|::.|:...:..||||||.|::||:|||.:|..
  Rat   358 DHAMIGPEGADNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQ 422

  Fly   447 RQRMLAKFTENDHEKVDRLLELHLKYLAKVEAIDKEIDQQAKD-----PTIDEDEEAENNYIKRL 506
            |.|:|.||||||.||||||:|||.|||..::..||:|:.:..|     ..||.|.|.| .|::||
  Rat   423 RTRLLNKFTENDSEKVDRLMELHFKYLGAMQVADKKIEGEKHDIVRRGEIIDNDMEDE-FYLRRL 486

  Fly   507 TGGLFTLQRIDYILLEV-SATGDTVKQRVLQILNLRGASMKTIRSIMREYAGNLGDG-DTDWREQ 569
            ..|||.||.|.||:.|: :|....::|||.||||:||:|:|.:|.|::|||.|:||| ..::||.
  Rat   487 DAGLFILQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRET 551

  Fly   570 EQNHILSLVDRF 581
            ||..||.|::.|
  Rat   552 EQKRILGLLENF 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11964	NP_649847.1	CTNNBL	87..553	CDD:462397	291/475 (61%)
Ctnnbl1	NP_001020041.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		31/112 (28%)
		Nuclear localization signal. /evidence=ECO:0000250	16..33		11/44 (25%)
		CTNNBL	57..534	CDD:462397	291/477 (61%)
		HEAT 1	79..129		31/49 (63%)
		Nuclear export signal (NES). /evidence=ECO:0000250	130..140		6/9 (67%)
		HEAT 2	134..176		25/41 (61%)
		ARM 1	178..228		36/49 (73%)
		ARM 2	229..273		29/43 (67%)
		ARM 3	274..323		33/48 (69%)
		ARM 4	325..363		30/37 (81%)
		ARM 5	364..417		32/52 (62%)