Protein Alignment Ir85a and grik4

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 811
• Identity: 145/811 - (17%)
• Similarity: 238/811 - (29%)
• Gaps: 320/811 - (39%)

  Fly    13 AILVNLAGTRENHIP-------------------LDLK-----------------KSSIVMVKMS 41
            :|:.|:.|.:|  :|                   |||:                 .||...:..:
Zfish   105 SIISNICGEKE--VPYVKVAPEDILKVQFPRFTTLDLRPTNTDISMAVAGLLTFFNSSTSCLICA 167

  Fly    42 QILCKARIKVLFVYFENQTSHEHTGQILKE---VTKCDISNQNTP-LEAVKDD------------ 90
            |..|...::||...|          .|.||   |...|.|...|| |:.::||
Zfish   168 QADCLLNLEVLLRQF----------LISKETLSVRMLDDSQDPTPLLKEIRDDKTATIIVDANAT 222

  Fly    91 ------------GIL-MYMVMITTNISQPLELSLIRKKSAAK-----------HRSHVF------ 125
                        |:| :|...|.|:    ||.||:|....|.           :|:|.|
Zfish   223 MSHVILERASELGMLSVYYTYILTS----LEFSLLRLDDLADQRVNIVGFSVFNRTHPFFQDFVL 283

  Fly   126 -----------------------LLVRDADTVSDAWMRASFRQ----------FWKIW-----LL 152
                                   ||.....||..|....:..|          ..|||     |:
Zfish   284 SLNRSWQENCDHAPFAGTPLSSALLFDAVHTVVAAVQELNRSQNVGATQLSCKSSKIWEHGTSLM 348

  Fly   153 NIVILYWRDGRLNAYRYNP--FMDNYLIPV-DNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDD 214
            |.:.:...:|......:|.  ...||.:.: .|..:.:..:.|...:...:|:||...:.:
Zfish   349 NYLRMVELEGLTGHIEFNSKGQRSNYALRIMQNSRDGLRQIGQWHSEQGLSMERKLPSLNV---- 409

  Fly   215 VRAIFWRQGTILGTDGLLAAYVAERLNATMMIT----RPH---SYNNHNLSSD-----ICFLEVA 267
                         ||.|        .|.|:.||    .|:   ..|:..|..:     .| :::.
Zfish   410 -------------TDTL--------FNTTLTITTILENPYVMLRANHQELEGNDRYEGFC-VDML 452

  Fly   268 KEYVDVAMNIRF-----LVPD----------TFRKQAESTVSHTRD----DLCVIVPKAKT---- 309
            ||..|:   ::|     ||.|          |:.......:|...|    .|.:...:.|.
Zfish   453 KELADI---LKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAEREKVIDFS 514

  Fly   310 ------------------APTFWNIFRSFGSLVWALILVSVLVANVFCYI--------------- 341
                              .|.:::....|...||..:|::.|..:...::
Zfish   515 KPFMTLGISIMYRVHIGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYNPHPC 579

  Fly   342 LKSEVGRVPMQL------------FAGALTMPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLT 394
            ||   ||..:.:            ..|.:....|..|...|.|.....|..|.|:|.|::..||.
Zfish   580 LK---GRCSLLINQYSLGNSFWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLA 641

  Fly   395 SMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMM 459
            :.:..|.....|..:..||.               |..:..|..|..... ...:.|..|.|:.|
Zfish   642 AFLTVQRMEVPIESVDDLAD---------------QTAIEYGTMHGGSTM-TFFQNSRYQTYQRM 690

  Fly   460 RNNDIRFAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCLVPFH------AVYI----------- 507
            .|    |.|.::..:........:...|.....:|:.|.:..::      ...|
Zfish   691 WN----FMYSKQPSVFVKSTEEGIARVLNSNYAYLLESTMNEYYRQRNCNLTQIGGLLDTKGYGI 751

  Fly   508 -VPYGSPYLGFLD-SLIRSSHEFGFE----RYWDRIMNSAFIKSGVKVV----NRRRGSGNDEPV 562
             :|.||.|....| :::|...|...|    ::||          |.|..    :|.:|.|
Zfish   752 GMPLGSVYRDEFDLAILRLQEENRLEILKRKWWD----------GGKCPKEEDHRAKGLG----- 801

  Fly   563 VLKLQHFHAVFAL----WLVGIGMACIVLAW 589
               :::...:|.:    .||.|.||.:...|
Zfish   802 ---MENIGGIFVVLVCGLLVAIFMAVLEFVW 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	57/311 (18%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	64/386 (17%)