Protein Alignment Ir85a and GluRIIE

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 110/593 - (18%)
• Similarity: 205/593 - (34%)
• Gaps: 149/593 - (25%)

  Fly    79 NQNTPLEAVKDDGILMYMVMITTNISQPLELSLIRKKSAAKHRSHVFLLVRDADTVSDAWMRASF 143
            :|.|  |:|:|||......|.|..::..|....|..:...:...|:.::......:
  Fly   333 SQRT--ESVRDDGSSFKNYMRTLRLTDRLLTGPIYFEGNVRKGYHLDVIELQPSGI--------- 386

  Fly   144 RQFWKIWLLNIVILYWRDGRLNAYRYNPFMDNYLIPV----DNKPNEVPTLEQLFPKTIPNMQRK 204
                      :.:..|.:.|    :|.|   ..|.|.    |:..|.:.....:...::||   |
  Fly   387 ----------VKVGTWDEDR----QYRP---QRLAPTTAQFDSVDNSLANKTFIILLSVPN---K 431

  Fly   205 PLRMCI--YKDDVRAIFWRQGTI----LGTDGLLAAYVAERL--NATMMITRPHSYNNHNLS--- 258
            |....:  ||.       .:|..    .|.|  |...:|::|  |.| .:...:.|.::|.|
  Fly   432 PYAQLVETYKQ-------LEGNSQYEGYGVD--LIKELADKLGFNFT-FVNGGNDYGSYNKSTNE 486

  Fly   259 SDICFLEVAKEYVDVAMNIRFLVPDTFRKQA-ESTVSHTRDDLCVIVPK-AKTAPTFWNIFRSFG 321
            |.....|:.....|:|  |..|...:.|:|| :.|:......:.::..| .|..|..:.....|.
  Fly   487 STGMLREIMTGRADLA--ITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFS 549

  Fly   322 SLVWALILVSVLVANVFCYILKSEVGRV--------------PMQL------------FAGALTM 360
            ..||..:..|.|..::..:||    ||:              |.:|            ..|||..
  Fly   550 EEVWWFLGFSFLGVSLSFFIL----GRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALLQ 610

  Fly   361 PMTQIPPNH-SIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPR 424
            ..::|.|.. |.|....||.:|.|::.|::..||.:.:..:.....||.:..||.:...::...:
  Fly   611 QGSEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAK 675

  Fly   425 HVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRNNDIRFAYLEKYHIARFQVNSRVHMHLGR 489
            .....::|...  ..|.|.::....:|:...|....|.:         .:.|.:.|:....
  Fly   676 KTGSTRNFFMT--SAEERYKKMNKFMSENPQYLTEDNME---------GVNRVKTNTHYAF---- 725

  Fly   490 PLFHLMNSCLVPFH------------AVYIVPYGS------PYLGFLDSLIRSSHEFGF-----E 531
                ||.|..:.::            |:....||.      |:.|..::.:....|.|.     .
  Fly   726 ----LMESTSIEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKN 786

  Fly   532 RYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACI--VLAW----E 590
            ::|:.:        |..:...:..:.:..|  |.:.:...||.:.|||...|.:  :::|    .
  Fly   787 KWWNEV--------GTGICATKEDAPDATP--LDMNNLEGVFFVLLVGSCCALLYGIISWVLFVM 841

  Fly   591 HLTHNYNL 598
            ...|:|.:
  Fly   842 KKAHHYRV 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	16/96 (17%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	77/408 (19%)
		Lig_chan	551..824	CDD:459656	53/305 (17%)