Protein Alignment Ir85a and Gria3

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_116785.2
• Gene: Gria3 / 29628
• RGDID: 70958
• Length: 888
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 89/492 - (18%)
• Similarity: 167/492 - (33%)
• Gaps: 111/492 - (22%)

  Fly   158 YWRDGRLNAY-RYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWR 221
            ||     |.| |:.||.|.. |..|:..:|..|:      .:..:...|..|  ||.:...:...
  Rat   392 YW-----NEYERFVPFSDQQ-ISNDSSSSENRTI------VVTTILESPYVM--YKKNHEQLEGN 442

  Fly   222 ---QGTILGTDGLLAAYVAERLNATMMITRPHSYNNHNLSSDI---CFLEVAKEYVDVAMNIRFL 280
               :|..:.....:|.:|  |:...:.|.....|...:..:.|   ...|:.....|:|     :
  Rat   443 ERYEGYCVDLAYEIAKHV--RIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIA-----V 500

  Fly   281 VPDTFRKQAESTVSHTRD----DLCVIVPK-AKTAPTFWNIFRSFGSLVWALILVSVLVANVFCY 340
            .|.|.....|..:..::.    .:.:::.| .|:.|..::........:|..|:.:.:..:|..:
  Rat   501 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 565

  Fly   341 IL------------KSEVGRVPMQ---------LF------AGALTMPMTQIPPNH-SIRLFLIF 377
            ::            .:|..|.|..         :|      .||.......|.|.. |.|:....
  Rat   566 LVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGV 630

  Fly   378 WLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESR 442
            |.:|.|:|.|::..||.:.:..:..:..|.....||:               |..:..| ..:|.
  Rat   631 WWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK---------------QTEIAYG-TLDSG 679

  Fly   443 IREQMLEVSDTQMYEMMRNNDIRFAYLEKYHIARFQVN-----SRVHMHLGRPLFHL---MNSCL 499
            ..::....|...:||.|      ::|::....:.|...     :||....|:..|.|   ||..:
  Rat   680 STKEFFRRSKIAVYEKM------WSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYI 738

  Fly   500 ---VPFHAVYI------------VPYGSPYLGFLDSLIRSSHEFGFERYWDRIMNSAFIKSGVKV 549
               .|...:.:            .|.||.....::..:....|.|.   .|::.|..:...|  .
  Rat   739 EQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGI---LDKLKNKWWYDKG--E 798

  Fly   550 VNRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACIV 586
            ...:.....|:...|.|.:...||.:.:.|:|:|.:|
  Rat   799 CGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMV 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Gria3	NP_116785.2	PBP1_iGluR_AMPA_GluR3	29..403	CDD:380610	6/15 (40%)
		PBP2_iGluR_AMPA	416..799	CDD:270433	69/424 (16%)