Protein Alignment Ir85a and GRIK5

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_011525167.1
• Gene: GRIK5 / 2901
• HGNCID: 4583
• Length: 982
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 70/337 - (20%)
• Similarity: 113/337 - (33%)
• Gaps: 98/337 - (29%)

  Fly   206 LRMCIYKDDVRAIFWRQGTILGTDGLLA-AYVAERLNATMMITRPHSYNNHNLSSDICFLEV-AK 268
            |||....||        .|:.|....|| |...|::|.                    .:|| ||
Human    24 LRMAAILDD--------QTVCGRGERLALALAREQING--------------------IIEVPAK 60

  Fly   269 EYVDVAMNIRFLVPDTFRKQAESTVSHTRDDLCVIVPKAKTAPTFWNIFRSFGSLVWALILVSVL 333
            ..|:|         |.|..|.:|.. .|.|.:|.|:||.                     :||||
Human    61 ARVEV---------DIFELQRDSQY-ETTDTMCQILPKG---------------------VVSVL 94

  Fly   334 VANVFCYILKSEVGRVPMQLFAGALTMPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMV 398
            ..:      .|......:....|...:|..::.|..:.||     .|......|.:..|....:.
Human    95 GPS------SSPASASTVSHICGEKEIPHIKVGPEETPRL-----QYLRFASVSLYPSNEDVSLA 148

  Fly   399 FQPYLPDINQLGA-LARSHYHIIIRPRHVKHIQHFL----TLGHK--HESRIREQML-EVSDTQM 455
            ....|...|...| |..:....::|...:  ::.||    ||..:  .:||....:| |:.|.::
Human   149 VSRILKSFNYPSASLICAKAECLLRLEEL--VRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKV 211

  Fly   456 YEMMRNNDIRFAYLEKYHIARFQVNSRVHMH----LGRPLFHLMNSCLVPFHAVYIVPYGSPYLG 516
            ..::.:.:...::|.....:...:.|..:.:    :..|:.||..          ||...|..||
Human   212 STIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDG----------IVEDSSNILG 266

  Fly   517 FLDSLIRSSHEF 528
            |  |:..:||.|
Human   267 F--SMFNTSHPF 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
GRIK5	XP_011525167.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	70/337 (21%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:473866