Protein Alignment Ir85a and Grin2c

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 572
• Identity: 100/572 - (17%)
• Similarity: 191/572 - (33%)
• Gaps: 236/572 - (41%)

  Fly   159 WRDGRLNAYRYNPFMDNY---LIP-VDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIF 219
            |..|.|  |...|....|   |.| ||::...|.|||:           :|..:....|.
Mouse   437 WDHGVL--YMKYPVWPRYSTSLQPVVDSRHLTVATLEE-----------RPFVIVESPDP----- 483

  Fly   220 WRQGTILGTDGLLAAYVAERLNATMMITRPHSYNNHNLSS-DI-----------CFLEVAKEYVD 272
                   ||.|.:...|..|           ..:||..|| ||           | :::.|:...
Mouse   484 -------GTGGCVPNTVPCR-----------RQSNHTFSSGDITPYTKLCCKGFC-IDILKKLAK 529

  Fly   273 VAMNIRF----------------------LVPDTFRKQAES-----TVSHTRDDLC-VIVPKAKT 309
            |   ::|                      ::.:.:.|:|:.     |::..|.::. ..||..:|
Mouse   530 V---VKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVET 591

  Fly   310 APTFWNIFRSFGSL------------VWALILV---SVLVANVFCY-----------ILKSE--- 345
            ..:.. :.||.|::            ||.::.|   :|:...||.:           :.|.:
Mouse   592 GISVM-VARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSG 655

  Fly   346 -----VGRVPMQLFAGAL--TMPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYL 403
                 :|:....|:|...  ::|: :.|...:.::.::.|.:|.::..:::..||.:.|:.:.|:
Mouse   656 GPSFTIGKSVWLLWALVFNNSVPI-ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYI 719

  Fly   404 PDINQL----------------------GALARS--------HYHII-IRPRHVKHIQHFLTLGH 437
            ..::.|                      |:..|:        |.|:: ...|.|:.....|.:|.
Mouse   720 DTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGA 784

  Fly   438 KHESRIREQMLEVSDTQMYEMMRNNDIRFAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCLVPF 502
            :|.||..:..  :.|..:...|...|                                ..|
Mouse   785 RHVSRKLDAF--IYDAAVLNYMAGKD--------------------------------EGC---- 811

  Fly   503 HAVYIVPYGSPYL----GFLDSLIRSSHEFGFERYWDRIMNSAFIK---------------SGV- 547
               .:|..||..:    |:..::.:.||       |.|.::.|.::               ||:
Mouse   812 ---KLVTIGSGKVFATTGYGIAMQKDSH-------WKRAIDLALLQFLGDGETQKLETVWLSGIC 866

  Fly   548 -----KVVNRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACIVLAWEHLTH 594
                 :|::.:          |.:.:...||.:.||.:|:|.:|.|||||.:
Mouse   867 HNEKNEVMSSK----------LDIDNMAGVFYMLLVAMGLALLVFAWEHLVY 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	4/10 (40%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	76/493 (15%)
		NMDAR2_C	905..>980	CDD:463148	2/4 (50%)