Protein Alignment Ir85a and Gria4

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_006509904.1
• Gene: Gria4 / 14802
• MGIID: 95811
• Length: 912
• Species: Mus musculus
• Alignment Length: 518
• Identity: 89/518 - (17%)
• Similarity: 165/518 - (31%)
• Gaps: 164/518 - (31%)

  Fly   158 YWRDGRLNAYRYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQ 222
            ||.|           ||..::..|     .|||                     .:|..||  ..
Mouse   389 YWND-----------MDKLVLIQD-----APTL---------------------GNDTAAI--EN 414

  Fly   223 GTILGTDGLLAAYVAERLNATMMITRPHSYNNHNLSSDICF---LEVAKEYVDVAMNIRFLVPD- 283
            .|::.|..:.:.||..:.|..|       :..::.....|.   .|:|| ::.:...|. :|||
Mouse   415 RTVVVTTIMESPYVMYKKNHEM-------FEGNDKYEGYCVDLASEIAK-HIGIKYKIA-IVPDG 470

  Fly   284 -------------------TFRKQ----AESTVSHTRDD------------LCVIVPK-AKTAPT 312
                               .:.|.    |..|::..|::            :.:::.| .|:.|.
Mouse   471 KYGARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 535

  Fly   313 FWNIFRSFGSLVWALILVSVLVANVFCYILK------------------------SEVGRVPMQL 353
            .::........:|..|:.:.:..:|..:::.                        :|.|......
Mouse   536 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW 600

  Fly   354 FA-GALTMPMTQIPPNH-SIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSH 416
            |: ||.......|.|.. |.|:....|.:|.|:|.|::..||.:.:..:..:..|.....||:
Mouse   601 FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK-- 663

  Fly   417 YHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRNNDIRFAYLEKYHIARF---- 477
                         |..:..| ..:|...::....|...:||.|      :.|:.....:.|
Mouse   664 -------------QTEIAYG-TLDSGSTKEFFRRSKIAVYEKM------WTYMRSAEPSVFTRTT 708

  Fly   478 -QVNSRVHMHLGRPLFHL---MNSCL---VPFHAVYI------------VPYGSPYLGFLDSLIR 523
             :..:||....|:..|.|   ||..:   .|...:.:            .|.||.....::..:.
Mouse   709 AEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVL 773

  Fly   524 SSHEFGFERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACIV 586
            ...|.|   ..|::.|..:...|  ....:.....|:...|.|.:...||.:.:.|:|:|.:|
Mouse   774 KLSEAG---VLDKLKNKWWYDKG--ECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLV 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
Gria4	XP_006509904.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	5/21 (24%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	68/416 (16%)