Protein Alignment Ir85a and grik3

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_031752773.1
• Gene: grik3 / 100498426
• XenbaseID: XB-GENE-6050069
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 687
• Identity: 120/687 - (17%)
• Similarity: 221/687 - (32%)
• Gaps: 208/687 - (30%)

  Fly    61 SHEHTGQILKEV--------------TKCDISNQNTPLEAVKDDGILMYMVMITTNISQPLELSL 111
            ||....|||::.              |..|:  ....||..:..|:.:....| .|:..|...|:
 Frog   234 SHTMAAQILRQAMAMGMMTEYYHYIFTTLDL--YALDLEPYRYSGVNLTGFRI-LNVDNPYVSSI 295

  Fly   112 IRKKSAAKHRSHV--------FLLVRDADTVSDAWMRASFRQFWKIWLLNIV-ILYWRDGRL--- 164
            :.|.|..:|::..        .::..||....||              ::|| :.|.|..::
 Frog   296 VDKWSMERHQATPKPESGLLDGIMTTDAALTYDA--------------VHIVSVCYQRAPQMTVN 346

  Fly   165 -------NAYRYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQ 222
                   .|:|:.....|:   :.....|..|...:|.||........|.:...|:|.   ..:.
 Frog   347 SLQCHRHKAWRFGSRFMNF---IKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDG---LEKV 405

  Fly   223 GTILGTDGL--------LAAYVAERL-NATMMITR--PHSYNNHNLSSDICF---------LEVA 267
            ||...:|||        ....::|.| |.|:::|.  ...|.....|....|         :::.
 Frog   406 GTWNPSDGLNITETARGRGPNISESLTNRTLIVTTVLEEPYVMFKRSDTPLFGKDRFEGFCIDLL 470

  Fly   268 KEYVDVA---MNIRFLVPDTFRKQAES----------------------TVSHTRD--------- 298
            |:..::.   .:||.:....:..|.|.                      |::|.|:
 Frog   471 KKIAEILGFDYDIRLVEDAKYGSQDEKGQWNGLVKELIDHKADLAVAPLTITHVREKVIDFSKPF 535

  Fly   299 ---DLCVIVPKAK-TAPTFWNIFRSFGSLVWALILVSVLVANVFCYILK---------------- 343
               .:.::..||. |||:.::........:|..||::.|..:...:::.
 Frog   536 MTLGISILYRKANGTAPSVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYDAHPCNPG 600

  Fly   344 SEVGRVPMQL-----FA-GALTMPMTQIPPNH-SIRLFLIFWLYFGLLICSAFKGNLTSMMVFQP 401
            ::|......|     || |||....:::.|.. |.|:....|.:|.|:|.|::..||.:.:..:.
 Frog   601 TDVVENNFTLLNSFWFAVGALMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVER 665

  Fly   402 YLPDINQLGALARS---HYHIII--------RPRHVKHIQHFLTLGHKHESRI----REQMLEVS 451
            ....|:....||:.   .|..::        :..|:...:..........|.:    .|.:..|.
 Frog   666 MESAIDSADDLAKQTKIEYGAVVDGATMNFFKKSHISTFEKMWAFMSSRPSALVKSNEEGIQRVL 730

  Fly   452 DTQMYEMMRNNDIRFAYLEKYHIARFQVNSRVHMH---LGRPLFHLMNSCLVPFHAVYIVPYGSP 513
            ......:|.:..|.  |:.:.:....|:...:...   :|.|:                   |||
 Frog   731 SADYALLMESTAIE--YITQRNCNLTQIGGLIDSKGYGIGTPM-------------------GSP 774

  Fly   514 YLGFLDSLIRSSHEFG-----FERYWDRIMNSAFIKSGVKVVNRRRGSG-----NDEPVVLKLQH 568
            |...:...|....|..     .||:|                   |..|     |.|...|.:|:
 Frog   775 YRDRISIAILQLQEADEIHKMKERWW-------------------RSGGCPEEKNKEASALGIQN 820

  Fly   569 FHAVFALWLVGIGMACIVLAWEHLTHNYNLAVTKRRD 605
            ...:|.:...|:.::.:|...|.:   |.|..|..|:
 Frog   821 MGGIFIVLAGGLILSVVVAMAEFV---YKLRKTAERE 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
grik3	XP_031752773.1	PBP1_iGluR_Kainate	37..417	CDD:380605	41/205 (20%)
		Periplasmic_Binding_Protein_Type_2	433..801	CDD:473866	63/407 (15%)