Protein Alignment Ir85a and grik5

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 784
• Identity: 143/784 - (18%)
• Similarity: 236/784 - (30%)
• Gaps: 306/784 - (39%)

  Fly     6 LKHILLLAILVNLAGTRENHIPLDLKKSSIVMVKMSQILCKARIKVL---FVYFENQTSHEHTGQ 67
            :.|||           :..|.|    .:|::..|..   |..|::.|   |:..::..|
 Frog   153 VSHIL-----------KSFHNP----STSLICAKAE---CLLRLEELVRQFLISKDTLS------ 193

  Fly    68 ILKEVTKCDISNQNTP-LEAVKDDGILMYMVMITTNISQPLELSLIRKKSA-----AKHRSHVFL 126
                |...|.||..|| |:.::||.:...::.....:|.     ||.||::     :.|..::..
 Frog   194 ----VRMLDESNDPTPLLKEIRDDKVSTIIIDANATVSH-----LILKKASELGMTSAHYKYILT 249

  Fly   127 -----------LVRDADTVSDAWMRASFRQFWKIWLLNIVILYWRDGRLNAYRYNPFMDNYLIPV 180
                       :|.|...:....|..|...|: :..|..:.:.||:        |..:..||.|.
 Frog   250 TMDFPLLSLEGIVSDQSNILGFSMYNSSHPFY-LEFLRSLNMSWRE--------NCELSTYLGPA 305

  Fly   181 -------D------------NKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQGTIL 226
                   |            |:..|: .::||...|                   :..|:.||.|
 Frog   306 LSAALMFDAVHVVVSAVRELNRSQEI-GVKQLSCST-------------------SQIWQHGTSL 350

  Fly   227 GT-------DGLLAAY----VAERLNATMMITRPHS---------YNNHNLSSDICFLEV----- 266
            ..       |||....    ..:|.|.|:.|.....         |:|..|:.:...|::
 Frog   351 MNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKAGDGHREIGVWYSNRTLAMNATSLDLSTSET 415

  Fly   267 ------------------------------------AKEYVDVAMNIRF-----LVPDTFRKQAE 290
                                                |:..:::|..:||     ||.|......|
 Frog   416 LENKTLVVTTILENPYMMRKSNYRSLSGNDQYEGFCAEMLMELAALLRFNYKIKLVEDGLYGAPE 480

  Fly   291 STVSHT---------RDDLCV-----------IVPKAK----------------TAPTFWNIFRS 319
            ...|.|         :.||.|           ::..:|                ..|.:::....
 Frog   481 PNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGRKPGYFSFLDP 545

  Fly   320 FGSLVWALILVSVLVANVFC------------------------YILKSE----------VGRVP 350
            |...||..:|::.|.  |.|                        :||:::          ||...
 Frog   546 FSPAVWLFMLLAYLA--VSCVLFLAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFM 608

  Fly   351 MQLFAGALTMPMTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARS 415
            .|   |:..||...     |.|.....|..|.|:|.|::..||.:.:..|.....|.....||.
 Frog   609 QQ---GSEVMPRAL-----STRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESADDLAD- 664

  Fly   416 HYHIIIRPRHVKHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRN--NDIR---FAYLEKYHIA 475
                          |..:..|..|..... ...:.|..|.|:.|.|  |..:   |....:..||
 Frog   665 --------------QTNIEYGTIHGGSTM-TFFQNSRYQTYQRMWNYMNSKQPSVFVKSTEEGIA 714

  Fly   476 RFQVNSRVHMHLGRPL--FHLMNSC-------LVPFHAVYI-VPYGSPY-----LGFLDSLIRSS 525
            |. :|||....|...:  :|...:|       |:......| :|.||||     |..|.....:.
 Frog   715 RV-LNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPYRDEITLAILQLQENNR 778

  Fly   526 HEFGFERYWDRIMNSAFIKSGVKVV----NRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACIV 586
            .|....::|:          |.|..    :|.:|.|        :::...:|.:.:.|:.:|..|
 Frog   779 LEILKRKWWE----------GGKCPKEEDHRAKGLG--------MENIGGIFVVLICGLIIAVFV 825

  Fly   587 LAWE 590
            ...|
 Frog   826 AIME 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	59/313 (19%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	72/396 (18%)