Protein Alignment Ir85a and grin3bb

DIOPT Version :10

• Sequence 1: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 729
• Identity: 132/729 - (18%)
• Similarity: 229/729 - (31%)
• Gaps: 262/729 - (35%)

  Fly    18 LAGTRENHIPLDLKKSSIVMVKMSQILCK-------ARIKVLFVYFENQTSHE--HTGQILKEVT 73
            ||....:|.|||...|..:.:....:...       |.|:.:...|:....||  .:||.:....
Zfish   302 LAYGEVDHKPLDFYISDALQLINRAVTAATVVRPDLALIQNMVNCFDKPNKHELPSSGQYIARFL 366

  Fly    74 KCDISNQNTPLEAVKDDGILMYMVMITTNISQPLELSLIRKKSAAKHRSHVFLLVRDADTVSDAW 138
                  .||....      |...|::..|:|          :....|:.|::.|.||| .....|
Zfish   367 ------SNTSFVG------LTGPVIVQRNLS----------RVHTSHKVHIWSLRRDA-VGQPTW 408

  Fly   139 MRASFRQFWKIWLLNIVILYWRDGRLNAYRYNPFMDNYLIPVDNKPNEVPTLEQLFPKTIPNMQR 203
                           :.:..|..||||......:.       .:.|.:         :|...|.|
Zfish   409 ---------------VTVGSWEGGRLNVEEQGLWQ-------GSSPRQ---------RTEGQMGR 442

  Fly   204 KPLRMCIYKDDVRAIFWRQG-TILGTDGLLAAYVAERLNATMMITRPHSY--------------- 252
            :..|            ||.| .:.|:          ||....::..|..:
Zfish   443 EGRR------------WRAGFPVSGS----------RLRVVTLVEHPFVFTREVDEDGNCPAGQY 485

  Fly   253 -----NNHNLSSDICFLEVAK----------------------EYVDVAMNIRF----------- 279
                 .|.:.:.|..:.|.|:                      |.:...||..|
Zfish   486 CLDAGTNSSETLDHLYAERAQGNKSFLPPDYSKCCYGYCIDLLEKLSEDMNFEFDLYIVGDGKYG 550

  Fly   280 ---------LVPDTFRKQAESTVSHTRDDLCVIVPKAK----TAPTFWN----IFRS------FG 321
                     ||.|.....|:..|:    ...:...::|    |:|.|..    :.||      .|
Zfish   551 AVKGGQWTGLVGDLLSGVADMAVT----SFSINSARSKVIDFTSPFFSTSLGILVRSKDTAAPIG 611

  Fly   322 SLVWAL-------ILVSVLVANVF--CYILKSEVG-------RVPMQLFAGALTM---------P 361
            :.:|.|       |.|::.:..:|  .|..||..|       ||.:..::.||.:         .
Zfish   612 AFMWPLHWSMWMGIFVALHITALFLTLYEWKSPFGMTPHGRNRVKVFSYSSALNLCYAILFGRTV 676

  Fly   362 MTQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVFQPYLPDINQLGALARSHYHIIIRPRHV 426
            .::.|...:.|..:..|..|.||:.|::..||.::||.:....:::.            |....:
Zfish   677 SSKTPKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVGEKTFEEVSG------------IHDAKL 729

  Fly   427 KHIQHFLTLGHKHESRIREQMLEVSDTQMYEMMRNNDIRF--------------------AYLEK 471
            .|.......|...||. .|..::.|..:|:|.||    :|                    |::..
Zfish   730 HHPSQGFRFGTVRESS-AEDYMKKSFPEMHEYMR----KFNEPTTPDGVATLKTDPPQLDAFIMD 789

  Fly   472 YHIARFQVNSRVHMHL---GRPLFHL--------MNSCLVPFHAVYIVPYGSPYLGFLDSLIRSS 525
            ..:..::|:......|   |:| |.:        .||.|....:.::..|.|.  |::|.|
Zfish   790 KALLDYEVSIDADCKLLTVGKP-FAIEGYGIGLPQNSPLTSNISEFVSRYKSD--GYMDML---- 847

  Fly   526 HEFGFERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPVVLKLQHFHAVFALWLVGIGMACIVLAWE 590
            |:     .|.::     :..|.:|.      ...|.:.:.::||..:|.|..||:..|.:.||.|
Zfish   848 HD-----KWYKV-----VPCGKRVF------AVTETLQMGIRHFSGLFVLLCVGVTGALLTLAGE 896

  Fly   591 HLTHNYNLAVTKRR 604
            |..:...|...:|:
Zfish   897 HAFYRLVLPHIRRK 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir85a	NP_649833.1	None
grin3bb	XP_017213803.2	Periplasmic_Binding_Protein_type1	39..427	CDD:471960	32/162 (20%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	74/427 (17%)
		Lig_chan	618..885	CDD:459656	57/306 (19%)