Protein Alignment Mkk4 and map2k6

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_073773990.1
• Gene: map2k6 / 65239
• ZFINID: ZDB-GENE-010202-3
• Length: 416
• Species: Danio rerio
• Alignment Length: 374
• Identity: 178/374 - (47%)
• Similarity: 239/374 - (63%)
• Gaps: 39/374 - (10%)

  Fly    66 QPQQTPPVASSQVPPVPAASSSSAA---------------DRHRERIRQQACGKLQFGEG----- 110
            |.::|..|..|::|.:.:.||.|.|               ||.::..::....|..|.:.
Zfish    46 QMEKTHLVLPSRLPLLHSLSSHSLALSHLPSQDLEPLGLSDRKKKLPKELKLPKEVFEKPAPAPT 110

  Fly   111 -------------GANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQ 162
                         |.......:||||..||:||||:|.|:||.......:|||||||:||:.:||
Zfish   111 PPRDLDSKAYVTIGEKNFVVKADDLEQIGELGRGAYGVVDKMRHVPSGVIMAVKRIRATVNTQEQ 175

  Fly   163 KQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICMELMDTSLDKFYKYIYEKQQRHIPESILAK 227
            |:|||||::.|::.:|.|.|.||||||:|||.||||||||||||||||.::|| .:.|||.||.|
Zfish   176 KRLLMDLDISMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYKQVHEK-GKTIPEDILGK 239

  Fly   228 ITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAP 292
            |||:.|.||.:|...|.:|||||||||:|::.:|.:|:|||||||.||||:|||.||||:|||||
Zfish   240 ITVSIVKALEHLHSNLSVIHRDVKPSNVLINMQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAP 304

  Fly   293 ERIDPE-RAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEF 356
            |||:|| ..|||:|:||:||||||::|:|...|||..|.:.|:||.|||:...|:|...    .|
Zfish   305 ERINPETNQKGYNVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPAD----RF 365

  Fly   357 SKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSHTDVAVYVADIL 405
            |.:||||.:.||.|..::||.|:.|::.||....::..||||.:|..||
Zfish   366 SADFVDFTSQCLRKNSTERPTYTELMQHPFFTLHDSKDTDVASFVKTIL 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	162/290 (56%)
map2k6	XP_073773990.1	None