Protein Alignment Mkk4 and map3k19

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_068079701.1
• Gene: map3k19 / 572217
• ZFINID: ZDB-GENE-081104-140
• Length: 1236
• Species: Danio rerio
• Alignment Length: 325
• Identity: 96/325 - (29%)
• Similarity: 148/325 - (45%)
• Gaps: 63/325 - (19%)

  Fly   103 GKLQ--FGEGGANTHTFTSDDLEDEGEI-GRGAFGAVNKMTFKKLDKVMAVKRI-----RSTVDE 159
            |||.  ||....:..|:|      :||: |:||:|.| ........:::|||::     .|.:.|
Zfish   944 GKLHYTFGSCSGDAITWT------KGEVLGKGAYGTV-YCGLTSQGQLIAVKQVALDASTSEIAE 1001

  Fly   160 KEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICMEL-----MDTSLDKFYKYIYEKQQRH 219
            ||..:|..::: ::|:.:...||.|.|....|....|.||.     :...|.:|         ..
Zfish  1002 KEYDRLEREVD-LLKNLKHTNIVGFLGTALSENIVSIFMEYIPGGSISNILGQF---------GP 1056

  Fly   220 IPESILAKITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGIS------------- 271
            :||.:....:...:..:.||... ::||||:|.:||:|...|.:||.|||.:
Zfish  1057 LPEKVFVLYSQQILEGVAYLHAN-RVIHRDLKGNNIMLMPTGVVKLIDFGCARRLSCLQTSTGSK 1120

  Fly   272 GQLVDSIAKTKDAGCRPY-MAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQ 335
            |.|:.|:..|      || ||||.|:   ..|:..:||:||:|.|:.|:|||..|....:.: ..
Zfish  1121 GDLLKSVHGT------PYWMAPEVIN---ETGHGRKSDIWSIGCTVFEMATGKPPLAHMNKM-AA 1175

  Fly   336 LCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSHTDVAVY 400
            |..:  |....|:.|.:. :||.:..|||..||.:.:..||....||..|||     ||...|.|
Zfish  1176 LYYI--GARRGLMPSLSD-DFSTDAKDFVQACLTRDQRQRPSAEELLRHPFI-----SHHSKACY 1232

  Fly   401  400
            Zfish  1233  1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	91/311 (29%)
map3k19	XP_068079701.1	ANKYR	<18..199	CDD:440430
		ANK repeat	43..73	CDD:293786
		ANK repeat	75..131	CDD:293786
		ANK repeat	133..177	CDD:293786
		STKc_YSK4	958..1224	CDD:270801	85/296 (29%)