Protein Alignment Mkk4 and GckIII

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_650596.1
• Gene: GckIII / 42064
• FlyBaseID: FBgn0266465
• Length: 642
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 99/318 - (31%)
• Similarity: 167/318 - (52%)
• Gaps: 41/318 - (12%)

  Fly   117 FTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLE---VVMKSNEC 178
            ||..:     .||:|:||.|.|....:..:|:|:|    .:|.:|.:..:.|::   :|:...:.
  Fly    13 FTKQE-----RIGKGSFGEVFKGIDNRTQQVVAIK----IIDLEEAEDEIDDIQQEIMVLSQCDS 68

  Fly   179 IYIVQFYGALFKEGDCWICMELM--DTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKE 241
            .|:.::||:..|....||.||.:  .::||......:|:....|   ||.::    :..|:||..
  Fly    69 PYVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGI---ILREV----LKGLDYLHS 126

  Fly   242 ELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKD-AGCRPYMAPERIDPERAKGYDV 305
            |.| :|||:|.:|:||..:||:||.|||::|||.::.:|... .|...:||||.|   :...||.
  Fly   127 ERK-LHRDIKAANVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVI---KQSQYDA 187

  Fly   306 RSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIK 370
            ::|:||||||.:|:|.|..|..:...: ..|..:.:..||:|..||     :|.|.|||..||.|
  Fly   188 KADIWSLGITAIELAKGEPPNSELHPM-RVLFLIPKNNPPQLTGSY-----TKSFKDFVEACLNK 246

  Fly   371 KESDRPKYSRLLEMPFIRRGETSHTDVAVYVADILESMEK----DGITQFTANQQAES 424
            ...:||....||:.|||::.:.:     .|:.|:::..:|    .|....|.::.::|
  Fly   247 DPENRPTAKELLKYPFIKKAKKN-----AYLIDLIDRFKKWKVSKGDESETESENSDS 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	95/293 (32%)
GckIII	NP_650596.1	STKc_MST3_like	12..283	CDD:270786	96/300 (32%)