Protein Alignment Mkk4 and stk25b

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_005171260.1
• Gene: stk25b / 406600
• ZFINID: ZDB-GENE-040426-2537
• Length: 430
• Species: Danio rerio
• Alignment Length: 296
• Identity: 96/296 - (32%)
• Similarity: 150/296 - (50%)
• Gaps: 36/296 - (12%)

  Fly   117 FTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLE---VVMKSNEC 178
            ||..:     .||:|:||.|.|....:..:|:|:|    .:|.:|.:..:.|::   .|:...:.
Zfish    20 FTKQE-----RIGKGSFGEVYKGINNRTKEVVAIK----IIDLEEAEDEIEDIQQEITVLSQCDS 75

  Fly   179 IYIVQFYGALFKEGDCWICMELM--DTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKE 241
            .|:.::||:..|....||.||.:  .::||..       :...:.|:.:|.|....:..|.||..
Zfish    76 PYVTKYYGSYLKGTKLWIIMEYLGGGSALDLL-------KPGPLEETYIATILREILKGLEYLHS 133

  Fly   242 ELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDS-IAKTKDAGCRPYMAPERIDPERAKGYDV 305
            |.| ||||:|.:|:||..:||:||.|||::|||.|: |.:....|...:||||.|   :...||.
Zfish   134 ERK-IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---KQSAYDF 194

  Fly   306 RSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIK 370
            ::|:||||||.:|:|.|..|......: ..|..:.:..||.|..||     ||.|.:||..||.|
Zfish   195 KADIWSLGITAIELAKGEPPNSDLHPM-RVLFLIPKNTPPTLEGSY-----SKPFKEFVEACLNK 253

  Fly   371 KESDRPKYSRLLEMPFIRRGETSHTDVAVYVADILE 406
            ....||....||:..||    |.:|....|:.::::
Zfish   254 DPRFRPTAKELLKHKFI----TRYTKKTSYLTELID 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	96/293 (33%)
stk25b	XP_005171260.1	STKc_MST3_like	20..291	CDD:270786	96/296 (32%)