Protein Alignment Mkk4 and map2k4a

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_073794208.1
• Gene: map2k4a / 403052
• ZFINID: ZDB-GENE-060512-98
• Length: 413
• Species: Danio rerio
• Alignment Length: 386
• Identity: 228/386 - (59%)
• Similarity: 282/386 - (73%)
• Gaps: 18/386 - (4%)

  Fly    36 STSSTSSGSTSSGSSSSSQH----NHVTRCFGAQQPQQTPPVASSQVPPVPAASSSSAA----DR 92
            :|||.||...|:.::.:..|    .|:|.....|..::...:..:. ||:...|..::.    :.
Zfish    22 ATSSPSSNPASASNNPAQLHPAQSQHITTMSSMQGKRKALKLNFAN-PPIKTTSRITSGLPFQNP 85

  Fly    93 HRERIRQ---QACGKLQFGEGGANTH-TFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRI 153
            |.||:|.   ::.|||:.   .|..| .||::||:|.|||||||:|:||||..|...::||||||
Zfish    86 HIERLRTHSIESSGKLKI---SAEQHCDFTAEDLKDLGEIGRGAYGSVNKMAHKPSGQIMAVKRI 147

  Fly   154 RSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICMELMDTSLDKFYKYIYEKQQR 218
            ||||||:|||||||||:|||:|::|.||||||||||:|||||||||||.||.||||||:|.....
Zfish   148 RSTVDEREQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSSLDE 212

  Fly   219 HIPESILAKITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKD 283
            .|||.||.|||:|||.|||:|||.|||||||:|||||||.|:|:|||||||||||||||||||:|
Zfish   213 VIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRKGNIKLCDFGISGQLVDSIAKTRD 277

  Fly   284 AGCRPYMAPERIDPERAK-GYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRL 347
            ||||||||||||||..:: |||||||||||||||.|:|||.|||.||:|||:||.|||:|:||:
Zfish   278 AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQ- 341

  Fly   348 LTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSHTDVAVYVADILESM 408
            |:|....:||.:|::|||.||.|.||.||||..||:..||:..|....|||.||..||:.|
Zfish   342 LSSSEERQFSPKFINFVNLCLTKDESKRPKYKELLKHAFIQMYEERSVDVATYVCRILDQM 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	204/291 (70%)
map2k4a	XP_073794208.1	None