Protein Alignment Mkk4 and stk4

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_989249.1
• Gene: stk4 / 394860
• XenbaseID: XB-GENE-955920
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 314
• Identity: 101/314 - (32%)
• Similarity: 173/314 - (55%)
• Gaps: 50/314 - (15%)

  Fly    92 RHRERIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRST 156
            ||.:::.:::..| |..|        ..|.||   ::|.|::|:|.|.:.|:..:::|:|:|..
 Frog    12 RHLKKLSEESLNK-QPEE--------VFDVLE---KLGEGSYGSVYKASHKETSQIVAIKQIPV- 63

  Fly   157 VDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICME------LMDTSLDKFYKYIYEK 215
              |.:.::::.:: .:|:..:.:::|::||:.||..|.||.||      :.|         |...
 Frog    64 --ESDLQEIIKEI-AIMQQCDSLHVVKYYGSYFKNTDLWIVMEFCGGGSISD---------IIRL 116

  Fly   216 QQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAK 280
            :::.:.|...|.|..:|:..|.|| ..::.||||:|..||||:..|..||.|||::|||.|::||
 Frog   117 RKQTLKEDETATILQSTLKGLEYL-HFMRKIHRDIKAGNILLNSEGTAKLADFGVAGQLTDTMAK 180

  Fly   281 TKDAGCRPY-MAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPYRK---WDSVFEQLCQVVQ 341
            .......|: ||||.|   :..||:..:|:||||||.:|:|.|..||.:   ..::|     ::.
 Frog   181 RNTVIGTPFWMAPEVI---QEIGYNCVADIWSLGITAIEMAEGKPPYAEIHPMRAIF-----MIP 237

  Fly   342 GEPPRLLTSYNGME-FSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIR--RGET 392
            ..||   .::...| :||:||||:|.||:|....|...:.||:.|||:  :||:
 Frog   238 SNPP---PTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPFIKTAKGES 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	96/291 (33%)
stk4	NP_989249.1	STKc_MST1_2	26..281	CDD:132943	93/290 (32%)
		SARAH_MST1	430..478	CDD:439181