Protein Alignment Mkk4 and Slik

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_726441.1
• Gene: Slik / 37893
• FlyBaseID: FBgn0035001
• Length: 1703
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 90/293 - (30%)
• Similarity: 146/293 - (49%)
• Gaps: 18/293 - (6%)

  Fly   126 GEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFK 190
            ||:|.||||.|.|...|: .|..|..::....||:.....:::::::.:... ..||:.|.|...
  Fly    41 GELGDGAFGKVYKAQHKE-QKRFAAAKMCQLEDEENLSDHMVEIDILSEIKH-PNIVELYEAFSI 103

  Fly   191 EGDCWICMELMD-TSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSN 254
            :...|:.:|..| .:||.    |..:.::.:.|..:|.:.......|.:|... |:||||:|..|
  Fly   104 DDKLWMLIEYCDGGALDS----IMVELEKPLTEPQIAYVCKHMTEGLTFLHRN-KVIHRDLKAGN 163

  Fly   255 ILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPY-MAPERI--DPERAKGYDVRSDVWSLGITL 316
            :||...|.:||.|||:|.:...::.|.......|| ||||.:  :..|...||.:.|:|||||||
  Fly   164 VLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITL 228

  Fly   317 MEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRL 381
            :|:|....|..:. |....|.::.:.|||:|   .....:||||.||:...|:|....||....|
  Fly   229 IELAQMEPPNSEM-SPMRVLLKIQKSEPPKL---EQPSRWSKEFNDFLKKSLVKDPQVRPTTDVL 289

  Fly   382 LEMPFIRRGETSH--TDVAV-YVADILESMEKD 411
            ::..||.|...:.  .|:.: |.|:::|.:..|
  Fly   290 MQHAFINRNLDAKPIKDLLLEYKAEVVEEVVDD 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	88/285 (31%)
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	86/279 (31%)
		PKK	958..1095	CDD:463600
		PKK	1126..1266	CDD:463600