Protein Alignment Mkk4 and mkk-4

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_509682.1
• Gene: mkk-4 / 185682
• WormBaseID: WBGene00003368
• Length: 363
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 164/369 - (44%)
• Similarity: 227/369 - (61%)
• Gaps: 44/369 - (11%)

  Fly    21 DQLSLNNLSIRHPPSSTSSTSSGSTSSGSSSSSQHNHVTRCFGAQQPQQTPPVASSQVPPVPAAS 85
            |:...|::|:|  |:|.|:..:..:.:|:                  ::|.|..|.
 Worm     6 DENLRNSMSLR--PTSLSTRPTSLSVNGN------------------EKTLPEESV--------- 41

  Fly    86 SSSAADRHRERIRQQACGKLQFGEGGANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAV 150
                       :|..:.|.|::.: ..:.:||:|.:|:|.|.||.|.||.|.||..|:..|::||
 Worm    42 -----------LRSLSTGTLKYPD-DEHLYTFSSANLQDLGAIGNGNFGTVYKMRHKETGKLIAV 94

  Fly   151 KRIR-STVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICMELMDTSLDKFYKYIYE 214
            |||| :.:..:||.:||.:.:.::||.:...||:||||:|.||||||||||||.|:|..||.:|.
 Worm    95 KRIRCNNIGHREQIRLLREHDTIVKSEKGPNIVKFYGAIFSEGDCWICMELMDISMDLLYKRVYM 159

  Fly   215 KQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIA 279
            .:...:.|:::..|||.||:||:|||:|||||||||||||||:...|.:|||||||.|||.:|.|
 Worm   160 VKNSRLNENVVGHITVCTVDALDYLKKELKIIHRDVKPSNILVDGTGAVKLCDFGICGQLEESFA 224

  Fly   280 KTKDAGCRPYMAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEP 344
            ||.||||:||:|||||  ..:..||||||||||||||.|:|||.|||::|:|:|:|:..||.|:|
 Worm   225 KTHDAGCQPYLAPERI--TSSDKYDVRSDVWSLGITLYEIATGKFPYQEWNSLFDQIATVVSGDP 287

  Fly   345 PRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIR 388
            |.|....:...:|...|.|:||||.|....||||..|....|.|
 Worm   288 PILHPDSDDFHYSLPLVKFINTCLTKDRRHRPKYDTLKSFDFYR 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	150/275 (55%)
mkk-4	NP_509682.1	PKc_MKK4	59..347	CDD:270790	150/275 (55%)