Protein Alignment Mkk4 and hpo

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_061498904.1
• Gene: hpo / 1276715
• VectorBaseID: AGAMI1_003228
• Length: 671
• Species: Anopheles gambiae
• Alignment Length: 301
• Identity: 99/301 - (32%)
• Similarity: 161/301 - (53%)
• Gaps: 25/301 - (8%)

  Fly   127 EIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSNECIYIVQFYGALFKE 191
            ::|.|::|:|.|...|:.::|:|:|::....|.:|   ::.::. :|:..:..|:|::||:.||.
Mosquito    31 KLGEGSYGSVYKALHKESEQVLAIKQVPVDTDLQE---IIKEIS-IMQQCDSPYVVKYYGSYFKN 91

  Fly   192 GDCWICMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELKIIHRDVKPSNIL 256
            .|.||.||.....   ....|...:::.:.|..:|.|.:.|:..|.||....| ||||:|..|||
Mosquito    92 TDLWIVMEYCGAG---SVSDIMRLRKKTLSEDEIATILIDTLKGLEYLHLRRK-IHRDIKAGNIL 152

  Fly   257 LHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPY-MAPERIDPERAKGYDVRSDVWSLGITLMEVA 320
            |:..|..||.|||::|||.|::||.......|: ||||.|:   ..|||..:|:||||||.:|:|
Mosquito   153 LNSEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE---EIGYDCVADIWSLGITALEMA 214

  Fly   321 TGNFPY---RKWDSVFEQLCQVVQGEPPRLLTSYNGME-FSKEFVDFVNTCLIKKESDRPKYSRL 381
            .|..||   ....::|     ::..:||   .|:...: :|.||:|||:.||:|...:|...:.|
Mosquito   215 EGKPPYGDIHPMRAIF-----MIPTKPP---PSFRDPDIWSPEFIDFVSLCLVKNPEERATATDL 271

  Fly   382 LEMPFIRRGETSHTDVAVYVADILESMEKDGITQFTANQQA 422
            |...|||..:.. :.::..:|:..|..|........|..||
Mosquito   272 LAHEFIRNAKPC-SILSQMIAEAKEIRENQSYRHAAAISQA 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	94/282 (33%)
hpo	XP_061498904.1	None