Protein Alignment Mkk4 and fray

DIOPT Version :10

• Sequence 1: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_309028.5
• Gene: fray / 1270343
• VectorBaseID: AGAMI1_005182
• Length: 552
• Species: Anopheles gambiae
• Alignment Length: 375
• Identity: 106/375 - (28%)
• Similarity: 164/375 - (43%)
• Gaps: 67/375 - (17%)

  Fly    42 SGSTSSGSSSSSQHNHVTRCFGAQQPQ-QTPPVASSQVPPVPAASSSSAADRHRERIRQQACGKL 105
            ||....|:|||:        .||.... |:...|:|     |:||:|||              .|
Mosquito     6 SGGVGGGASSSA--------LGAMAAAVQSVAAAAS-----PSASASSA--------------NL 43

  Fly   106 QFGEGGANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLE 170
            ............:.||.|....||.||...|:........:..|:|||..........:||.:::
Mosquito    44 APPPQPITPWPNSRDDYELNDVIGVGATAVVHNAYCLPRKEKCAIKRINLEKWNTSMDELLKEIQ 108

  Fly   171 VVMKSNECIYIVQFYGALFKEGDCWICMELMD--TSLDKFYKYIYEKQQRHIPESILAKITVATV 233
            .:...|. ..:|.::.:...:.:.|:.:.|::  :.||.....:.....||   .:..:.|:|||
Mosquito   109 AMSSCNH-ENVVTYHTSFVVKEELWLILRLLEGGSLLDIIKHRMRTVNCRH---GVFDEPTIATV 169

  Fly   234 NALNYLKEELK---------IIHRDVKPSNILLHRRGDIKLCDFGIS------GQLVDSIAKTKD 283
                 |||.||         .||||:|..||||...|.:::.|||:|      |.|.....:...
Mosquito   170 -----LKEVLKGLEYFHSNGQIHRDIKAGNILLGDDGTVQIADFGVSAWLATGGDLSRQKVRHTF 229

  Fly   284 AGCRPYMAPERIDPERAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLL 348
            .|...:||||.:  |:..|||.::|:||.|||.:|:|||..||.|:..: :.|...:|.:||.:.
Mosquito   230 VGTPCWMAPEVM--EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-KVLMLTLQNDPPTID 291

  Fly   349 TSYNGME-------FSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGE 391
            |   |.|       :.|.|...:..||.|:.:.||..|.||:.||.::.:
Mosquito   292 T---GAEEKDQYKAYGKTFRKLIGECLQKEPTKRPTASELLKHPFFKKAK 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	88/301 (29%)
fray	XP_309028.5	None