| Sequence 1: | NP_001262373.1 | Gene: | 5-HT2B / 41017 | FlyBaseID: | FBgn0261929 | Length: | 947 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036985.2 | Gene: | Htr4 / 25324 | RGDID: | 2850 | Length: | 388 | Species: | Rattus norvegicus |
| Alignment Length: | 223 | Identity: | 81/223 - (36%) |
|---|---|---|---|
| Similarity: | 123/223 - (55%) | Gaps: | 33/223 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 75 YWALLALVLVLGTAAGNILVCLAIAWERRLQNV-TNYFLMSLAITDLMVAVLVMPLGILTLVKGY 138
Fly 139 FPLGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSL-RYPMRFGRNKTRRRVTLKIVFVWLLSI 202
Fly 203 AMS-LPLSLMYSK------------NHASVLVNGT-C--QIPDPVYKLVGSIVCFYIPLGVMLLT 251
Fly 252 Y---CLTVRLLARQRQNLGGGQQTAAAT 276 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| 5-HT2B | NP_001262373.1 | 7tmA_5-HT2_insect-like | 74..>267 | CDD:320433 | 76/212 (36%) |
| TM helix 1 | 75..101 | CDD:320433 | 8/25 (32%) | ||
| TM helix 2 | 108..134 | CDD:320433 | 16/25 (64%) | ||
| TM helix 3 | 146..176 | CDD:320433 | 18/30 (60%) | ||
| TM helix 4 | 188..211 | CDD:320433 | 6/23 (26%) | ||
| TM helix 5 | 229..258 | CDD:320433 | 12/31 (39%) | ||
| 7tm_GPCRs | <799..893 | CDD:475119 | |||
| TM helix 6 | 818..840 | CDD:410628 | |||
| TM helix 7 | 854..879 | CDD:410628 | |||
| Htr4 | NP_036985.2 | 7tmA_5-HT4 | 20..323 | CDD:320184 | 81/223 (36%) |
| TM helix 1 | 21..47 | CDD:320184 | 8/25 (32%) | ||
| TM helix 2 | 55..81 | CDD:320184 | 16/25 (64%) | ||
| TM helix 3 | 93..123 | CDD:320184 | 18/29 (62%) | ||
| TM helix 4 | 136..159 | CDD:320184 | 6/22 (27%) | ||
| TM helix 5 | 189..218 | CDD:320184 | 11/29 (38%) | ||
| TM helix 6 | 252..282 | CDD:320184 | |||
| TM helix 7 | 291..316 | CDD:320184 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||